At 1 to 1000 mcg/mL it dose dependently inhibits DAT and even some NET at the higher doses. This is of the whole extract it seems.
http://www.ncbi.nlm....ubmed/18485464/
Plasma concentrations may be somewhere in the range of this with injection, but I like to assume a factor of 2 due to absorption delays and metabolism. For 5 liters of blood, that is an upper limit of 2*5*.001g*1000mL/L = 10 grams. Since this is a 5:1 extract, I should be able to see the full effect with 10/5*1.2 = 2.4 grams for my body weight (having 20% more blood than the average joe).
I just did some math on the scoop, and it seems that this batch is a little more dense. It's about 1.1 grams per scoop. I'll try two very slightly mounded scoops tomorrow morning to get my 2.4 grams. My guess is that I need a higher dose than even that over time due to enzyme adjustment... This is already an uncomfortably large dose for the price. Even if I get an hour of noticeable (side) effects, will it be enough to correct ADHD symptoms for the rest of the day? Will that work for chronic use as well? If so, what dose will this work all day into the next? Or if not, what is the half life of all system corrections? I hope to learn as much of this before I run out.
Another trick I noticed works with catecholamine reuptake inhibitors is synergizing caffeine or a release agent to kick in at around the same time. That way, more dopamine/norepinephrine is pooled in the CNS. I did this with Strattera+Caffeine and also Phenylpiracetam with itself by spacing out the doses. If there is also a release agent effect with Mu Gua, the effect will be more of a steep S shaped curve until the release agent effect is maxed for dose response rather than linear or straight exponential. Anyhow, since the effects kicked in so quickly, I'm willing to bet that I'd be better off drinking my coffee first. Or sandwiching my coffee in between the two doses.
Edited by devinthayer, 15 August 2016 - 03:16 AM.