27 replies to this topic

[ageless]

Anyone try this yet?... I bought two bottles and will soon begin trying it out. Time-released R-Lipoic Acid that is very stable.

[kenj]

I take 1 cap first in the evening... I don't know if I should take more to replace the other Lipoic Acid's; - they also give a milder sustained effect during the day:

So far I got 1 cap of Geronova's R-PLUS with my Mito Energy Optimizer (4 caps) in the morning and later Ortho-Mind (4 caps), that'll pop intake to some 510s'mg.

[FunkOdyssey]

Geronova's R-Lipoic Acid supplements are also sustained release formulas, and have the added bonus of including R-dihydrolipoic acid. Is there anything about AOR's formula that is superior and would potentially offset the lack of R-DHLA?

[kenj]

AOR say it 1) "is formulated in a special matrix to provide a sustained release guaranteed for 8-10 hours" and 2) is "specially formulated with a more bioavailable salt form than the conventional “alpha lipoic acid” or R+ Lipoic acid".

[xanadu]

Is a time release form neccessary? Is it worth it? I hear regular ala has 50% r-ala in it so just take twice as much of the cheap stuff.

[Pablo M]

Did you buy your R+SR from a Canadian source?

[kenj]

Is it worth it?

Well, no more setting alarms to 1.10 AM and 3.45 AM dosing Lipoic Acid's...

Did you buy your R+SR from a Canadian source?

AOR in europe.

[curious_sle]

What would be a good place to buy it and is it even smart to take this kind of dosage at age 30?

Plus how to deal with ALCAR? What is the serum lifetime of ALCAR anyway?

[psychenaut]

AOR is advising as of today that R+ SR availability in the USA is about the end of Feb or 1st of March.

Sure, save a buck. Buy the ALA for oral use. Spike your plasma levels at :45 min, be back down to baseline in 1:30hr. Dose 16 times a day to obtain some sembalance of a steady plasma level. That is a great way to save money (Wrong!). To each his own I suppose.

Oh yeah- keep on jamming your bodys receptors with that unnatural S enantiomer in the ALA. It is a chiral universe and some people just refuse to comprehend that fact. But you sure look stupid trying to tug that left handed glove onto your right hand all day long.

My belief regarding RLA dose is let your wallet be your guide. My current thinking is that RLA/DHLA and astaxanthin are the perfect antioxidant combo. I remain at 600mg lipoic daily composed of one each Mito-Gold /R-Plus in morning and evening along with 24mg total astaxanthin.

The DHLA recycles the RLA resulting in potentiated antioxidant effect, and additional, natural, time-release effect. Your body wants time-release, not two spikes once a day.

I must confess to a degree of frustration and amazement that on this forum of all places, there remains such an understanding gap of the benefits of a stable, time-release r-lipoic.

As always, I am available by phone for anyone caring to discuss this in greater (or lesser! [g:)]) depth. Or use the search feature in my blog, or use the "Learn" page on my site.

Cheers,
Pete

[kerastasey]

AOR say it 1) "is formulated in a special matrix to provide a sustained release guaranteed for 8-10 hours" and 2) is "specially formulated with a more bioavailable salt form than the conventional “alpha lipoic acid” or R+ Lipoic acid".

I don't know how that compares to Geronova, but I thought MCT-stabilised had that sort of release profile. The second part doesn't imply any superiority over the Geronova R-lipoics.

curious_sle - do you mean where to get it outside the US? I want that too. Relentless Improvement sells it in the US but I find it expensive, too much including importing to Europe. Until I find a source I just disperse KRala in water and drink it throughout the day. It's vial, but cheap, and should maintain some kind of higher plasma level.

[Pablo M]

Well, no more setting alarms to 1.10 AM and 3.45 AM dosing Lipoic Acid's... 

Wouldn't the disruption to your sleep cycle negate any benefits from taking the lipoic acid?

R(+) SR is specially formulated with a more bioavailable salt form than the conventional “alpha lipoic acid” or R+ Lipoic acid and is more stable to heat and moisture making it more resistant to polymerization.

Hmm, not exactly strong praise of AOR's own r-lipoic acid product.

I just finished a lot of back-and-forth with Natural Factors, trying to determine if their "8 hour time-release" vitamin C product really maintainied appreciable plasma levels for 8 hours. Long story short-- they don't know.

[hallucinogen]

Gawd, this stuff is expensive ehh! But I'm happy, just got 3 bottles coming from AOR...
So! Anyone know of any cheap sources yet? AOR says they only ship it in Canada as of now.

[ageless]

It's actually not that expensive IMO... compared to other K-RLA etc... time-released and stable make it all worthwhile.
I love this stuff so far... AOR R+(SR) is the only R-LA I would consider taking. I esp. like taking it around my workout schedule and my workouts have been going great and I feel great.

[hallucinogen]

Oooo sweetneSs, this stuff is granulated in caps, makes me feel better just by looking at it!

Edited by hallucinogen, 29 January 2006 - 07:49 AM.

[liorrh]

regular KRALA has a half hour of 8 hours.

[curious_sle]

curious_sle - do you mean where to get it outside the US?  I want that too.  Relentless Improvement sells it in the US but I find it expensive, too much including importing to Europe.  Until I find a source I just disperse KRala in water and drink it throughout the day.  It's vial, but cheap, and should maintain some kind of higher plasma level.

Um, well. If there was a decent place in europe to get this stuff i'd love to know but for the time beeing my AOR supplier of choice remains relentlessimprovement. I shure hope my country finally nails the freetrade agreement so i can cut out the tax bill for my small imports. Alternatively if i knew more about legality of what i import (so far noone objected :-) ) i'd maybe even get some small reseller shop open which would at least up my possibilities to consume as much of what i want as i'd like to but since i don't want to get broke on mostly unproven items i limit myself to a decent budget for this stuff. Damn i'd love to have custom made products since i find it troublesome to count and measure doses daily and i really swallow a lot it would seem t me but compared to many in here it's minimal really... aw...

[kevink]

regular KRALA has a half hour of 8 hours.

I assume you mean "half life" not "half hour"?

If that is what you meant - are you sure about that?

[hallucinogen]

regular KRALA has a half hour of 8 hours.

What is the source of your misleading information?

Edited by hallucinogen, 29 January 2006 - 08:08 PM.

[liorrh]

spare me your propheanities and exclamations and prove your point with references and logic an not with childish sophism.

[hallucinogen]

spare me your propheanities and exclamations and prove your point with references and logic an not with childish sophism.

That's what I just asked you to do! take some nootropics:p

[alexoverhere]

I've been taking Geronova's R-ALA gel product. It's somewhat expensive.

Some bulk suppliers are selling their new stable powder product http://geronova.com/RLA-MCT25.htm more cheaply.

[liorrh]

spare me your propheanities and exclamations and prove your point with references and logic an not with childish sophism.

That's what I just asked you to do! take some nootropics:p

you edited your post!

your post originaly was a childish reaction. now its a calm questioning.

that's being a jerk.

ach forget about it. I'm not going any further with this moronicity.

now:
regarding the information
this is what I recall, and I'll bring evidence when the avant site will be up.
regardless if I prove it or not, you have to prove your point too for mine to become false. currently my theorem is not true or false.

logic, my friend. not that hard.

[hallucinogen]

Keep it professional.

[vastman]

Hallucinogen, kenji, ageless or anyone else having the good fortune of acquiring R+ (SR)... please let me know if you've found a supplier who will ship to me in California. I've been waiting for this product since I learned of it a few months ago.... Any info would be much appreciated.

Well, for those of you in my boat, I just did an updated google search and found it at the following :
www.victoriashealth.com/shopping/products.aspx?by=brand&value=AOR - 65k -, a Canadian company. It costs 39.95 us dollars and to avoid shipping I had to order over $200, or 6 bottles... there went my fun money for the month!!! Can't wait to begin flooding my system with this lovely stuff..... YIPPEE!!!!!

Edited by vastman, 04 February 2006 - 09:36 PM.

[xanadu]

I'll wait until the fad is over and the price comes down. Meanwhile, I'll use my plain ordinary ala that has been proven to work fine.

[angelfire]

It's 22 min half life, isn't it [KRala]?

[trh001]

I've been taking LEF's R-Dihydro-LA. The contents contain, in addition to the active ingredient, "gelatin, MCT (medium chain triglyceride) oil, rosemary extract, and ascorbyl-palmitate." How different is this from

http://www.geronova.com/RALA-Gel.htm

Seems to be a similar matrix for enhanced absorption. Meanwhile LEF's product has 150mg of RDHLA, where as Geranova has only a mixture of 100mg of RLA and DHRLA in unspecified ratio:


RALA-Gel®,contains:

100 mg RLA/R-DHLA

350 mcg D-Biotin

medium chain triglycerides

Bottles of 60 and 120 liquid-filled, vegetarian capsules at our online store.

....cost is $34.95 for 60 caps, where as LEF sells it's product (50% more per capsule of RDHLA, relative to an ill-defined ratio of RLA and RDHLA) for $31.50 to members.

[Shepard]

RALA-Gel is 66mg RLA, 34mg R-DHLA. There are some past arguments why RLA is necessary when ingesting R-DHLA.