"Here, we report that the TALE homeoprotein TGIF2 acts as a developmental regulator of the pancreas versus liver fate decision and is sufficient to elicit liver-to-pancreas fate conversion both ex vivo and in vivo."
"Our data show that TGIF2 functions as a versatile reprogramming factor, exerting a twofold activity: it unlocks and represses hepatic identity and establishes pancreatic cell identity."
http://www.nature.co...les/ncomms14127
