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NON-synthetic/xenobiotic nootropics?


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#1 ajnast4r

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Posted 26 February 2006 - 08:16 PM


seems like all nootropics are synthetic or completely xenobiotic... are there any naturally occuring noots?

the only ones i could come across were galantamine & hup-A, both of which i do not beleive are acceptable for daily/long term use in healthy young people because they inhibit acetylcholinesterase...

#2 xanadu

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Posted 26 February 2006 - 08:22 PM

Bacopa

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#3 LifeMirage

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Posted 26 February 2006 - 08:24 PM

Naturally occuring without any chemical changes:
Alpha GPC
Vincamine
CDP-Choline
Huperzine A
Galantamine
Vasopressin

Made/based from natural compounds but does not occur naturally:
Vinpocetine
Pyritinol
Idebenone
Piracetam
Deprenyl
Picamilon
Centrophenoxine

Many nootropics are modified vitamin compounds with a remarkable degree of safety.

#4 ajnast4r

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Posted 26 February 2006 - 09:23 PM

thanks for the list ;)

vincamine is what vinpocetine is made from right? what is the difference & how do they fair against one another?

#5 FunkOdyssey

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Posted 27 February 2006 - 03:52 PM

That's a great question, worthy of a...

*bump*

#6 LifeMirage

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Posted 27 February 2006 - 04:22 PM

Vincamine half-life is about 9 hours, while vinpocetine's is 2 and a half. Vincamine has been studied and shown effective in treating dementia, vinpocetine has not.

#7 dimjimm

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Posted 27 February 2006 - 06:45 PM

IIRC Hydergine and Nicergoline were isolated from some sort of fungus.

#8 mitkat

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Posted 28 February 2006 - 04:34 AM

I believe hydergine, nicergoline and possibly bromo are all synthesized from the infamous ergot fungus.

#9 simple

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Posted 01 March 2006 - 12:40 AM

LIFEMIRAGE, so what would be the ideal Vinpocetine amount that you have to take to have an effect? and how often ?

#10 LifeMirage

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Posted 01 March 2006 - 12:47 AM

LIFEMIRAGE, so what would be the ideal Vinpocetine amount that you have to take to have an effect? and how often ?


If no other cerebral vasodilators were taken I would recommend 20-40 mg daily with meals taken in at least 2 doses. Although you may use a 20-40 mg dose at once to increase the chance of seeing an immediate effect.

#11 FunkOdyssey

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Posted 01 March 2006 - 02:51 AM

Why would you want to take vinpocetine if vincamine can do the same thing with a half-life of nine (!!!) hours? Does vinpo have some wonder effects that vincamine can't produce? Also, what dosage would you recommend if vincamine was the only vasodilator used?

#12 Shepard

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Posted 01 March 2006 - 03:52 AM

From my understanding, vincamine is a more powerful mental stimulant, but vinpocetine increase CBF more.

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#13 LifeMirage

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Posted 01 March 2006 - 05:37 PM

Correct




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