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[stefan_001]

Mechanisms of Ketogenic Therapy: Evidence for Increased NAD+
https://www.frontier...2017.00377/full

KD + NR may be a powerfull health combination to test.

[HaplogroupW]

I didn't know that glucose consumes 4x as much NAD+ as BHB per acetyl-CoA that gets produced:

 

 

NAD exists in oxidized and reduced forms, NAD⁺ and NADH, respectively, and whereas both glucose and ketone pathways each produce two molecules of acetyl-CoA, glucose reduces four molecules of NAD⁺ and ketone bodies reduce either one (β-OHB), or none (AcAc) during acetyl-CoA synthesis

 

Though more of the energy on a KD is from fatty acid beta oxidation than from ketones. From wikipedia, it looks like beta oxidation is not quite as advantageous as BHB metabolism in that one NAD+ is reduced per acetyl-CoA molecule produced, (but still better than glucose which reduces two NAD+ for each acetyl-CoA):

https://en.wikipedia.../Beta_oxidation

 

 

 

Edited by HaplogroupW, 27 November 2017 - 05:07 AM.