I"ve been ignoring the info around...I think taking EPA without DHA or with minimal DHA is what is recommended (I'm just taking....thorne or tyler fish oil). perhaps asvoiding DHA is a bad idea:
Neurobiol Aging. 2003 Mar-Apr;24(2):233-43. Related Articles, Links
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DHA-enriched phospholipid diets modulate age-related alterations in rat hippocampus.
Favreliere S, Perault MC, Huguet F, De Javel D, Bertrand N, Piriou A, Durand G.
EA 1223 G.E.M.C.I., Faculte de Medecine et Pharmacie, 86005 Poitiers, France. s.favreliere@voila.fr
Our previous work on rat hippocampus showed that a loss of docosahexaenoic acid (DHA) occurs in the fatty acid composition of phosphatidylethanolamine (PE), plasmenylethanolamine (PmE) and phosphatidylserine (PS) with increasing age. The present study investigated whether a DHA-enriched phospholipid dietary supplement could restore DHA levels and cholinergic activity. Male rats were fed a balanced diet containing both linoleic and alpha-linolenic acids until the age of 2, 18 and 21 months. From 18 to 21 months, one subgroup received a diet supplemented with DHA-enriched phospholipids from egg yolk (E-PL), and another a diet with DHA-enriched phospholipids from pig brain (B-PL). Compared to the control diet, the E-PL diet restored the proportion of polyunsaturated fatty acids (PUFAs: 22:6n-3 and 20:4n-6) in PE and PmE, while enhancing spontaneous and evoked-acetylcholine (Ach) release. The B-PL diet had no effect on PUFAs, but increased basal extracellular levels of Ach in 21-month-old rats as compared to the age-matched control. Our results show that supplementation with DHA-enriched egg PL can enhance Ach release and correct PUFA composition.
PMID: 12498957 [PubMed - indexed for MEDLINE]
