I had only ever heard of resveratrol and stillbenes acting via SIRT1 activation. But this recent result shows impressive effects, including increased telomere length, of resveralogues duplicated in each of 3 lines of human fibroblast cells:
https://bmccellbiol....2860-017-0147-7
We found that cells treated with resveratrol or any of the novel resveralogues had telomeres that were 1.3–2.4 times longer than vehicle-only controls, compared with younger cells at PD25, which showed telomeres 2.6 times longer than untreated senescent cells (Fig. 5c).
Also, it shows that it rescued SASPs from the senescent state.
I wasn't paying attention through the whole resveratrol episode, which I've heard described as a debacle. Has it totally fallen out of favor?