Dirk_Diggler, on 05 October 2011 - 05:39 PM, said:
Ampa-omega, on 05 October 2011 - 04:29 AM, said:
anyways why is it that only 4 racetams (pira,ani,oxi,prami) are usually sold and the others not? can someone explain that to me
Because those are the ones that have been studied the most. When you take something that has little human studies, you are really taking a huge risk.
BTW, nefiracetam just sounds like it would do something that would make your nuts fall off. Nefiracetam? Everytime I hear that I just think of Nosferatu for some reason...
The sound of nefiracetam has always reminded me of death a little bit. I'm guessing because it contains similar sounds as necrosis or necrophilia? Yeah, maybe it's more indicative of personal subconscious states... whatever
I had a detailed post about nefiracetam written when my browser crashed.... but I may as well rewrite it since there's all this speculation going on. I think ignorance and fear is the main reason that keeps people from considering the benefits of nefiracetam.
First of all I disagree with correlating toxicity studies done on dogs with humans. Mainly because there are quite a few commonly ingested substances that have highly toxic reactions on dogs. Coffee and chocolate cause kidney damage in canines right?
Anyway, the human equivalent for the lower oral dosages from the dog study
would be a little over 7,000mg / day. (180mg/kg for 8kg dog is about 7,300mg for 70kg human) You can use this allometric scaling calculator
to make these conversions from animal to human dosages even if you don't understand it, just fill in the blanks. (I hope I did that right)
Phase 2b human trials with nefiracetam are currently being conducted by Neuren Pharmaceuticals, marketed as Motiva
for post stroke apathy at dosages up to 900mg.
There is potential for nefiracetam as a treatment for addiction as well. I noticed the benefits while experimenting personally and I think it may have something to do with the cAMP related activity per this study
which stopped self administration of morphine and methamphetamine in rats.
I found an effective dose at 150mg three times per day. If you want more detailed report you can see my other post
, or for very thorough speculative toxicity research, and some interesting studies on nefi's nicotinergic mechanisms by Chrono go here