AgeVivo, on 09 January 2012 - 09:22 PM, said:
What is his view on how to rapidly live longer and healthier?
- For compounds that are available and well known and already demonstrate good health effects (like metformin or other to come soon from the ITP or Spindler), do we have the appropriate context now to investigate with AAA their global health effects in 2012
- in aged persons?
- in cats and dogs? for petfood to promote the meme
- For longevity genes that are already in long lived humans, like special versions of APOE, IGF1 and FOXO3a, do we have now the appropriate context to investigate with AAA their therapy in volunteers who do not have those genes?
- To assess other genes/compounds/interventions, how can we boost ITP/Spindler like studies?
- How can we boost more fondamental research against aging, like SENS?
- Following the numerous young-blood rejuvenating factor studies of this year, do we have now the appropriate context to investigate if aged persons who received blood from young donors get a benefit?
- Would he know AAA plans regarding the points above?
Kevin, I know I'm a bit pushy with such questions, but that's your goal in life too and hey time is passing so fast if we don't act
At 48 years old (I was 40 when I joined ImmInst) no one is more acutely aware of the passage of time, I assure you!
Do not apologize for being impatient with the slow progress that has been made given the huge potential that exists...
The questions you ask are great scientific and experimental strategy questions, and could discuss them at great length, but I would propose that perhaps they are not the most pertinent in moving the mission forward. What we need is more funding and manpower focused on the problem, there is no shortage of ideas. In essence we need to have 10% of the population of the United States believing in the importance and potential of real aging interventions. This is a scientifically validated percentage of a population that needs to hold a deeply held belief to get to a tipping point which would then see the entire public supporting a movement to combat degenerative disease. The science will come.
We need to continue to push hard to raise public awareness using social media and all other available avenues about what is really possible with new and emerging technologies and knowledge. The status-quo is not going to deliver the goods in a time frame that most of us would be happy with and we need to innovate to tap into the energy of those who are the most motivated to get things done, the patients and their caregivers. The Science is there to be discovered, we have proofs of principle that can serve as poster children to advocate for resources. As a senior biogerontologist I know said, "We need marketing."
Thanks all for the opportunity to share.