I had high hopes for boswellia as a treatment for what I suspect may be chronic inflammation (with a neuroinflammatory component). Curcumin worked well (....almost as well as DOI or ayahuasca), but also immediately did away with sex drive. Boswellia seemed better at first (300 mg per day initially, then lowered to 150), but after two or three days I began to become tired and quite depressed, which seemed to abate with reduction of boswellia. The only mechanism I was able to find that might be implicable would involve effecting the cortisol cortison balance
I'm perplexed as to the mechanism and am wondering if anyone is aware of a disease-state in which a decrease in inflammation might be pro-depressive?