19 replies to this topic

[alex172]

Hello, I want to ask one question I can not find a detailed answer. 

 

I understand that people already making efforts / Developing theories to achieve a cure for aging.

 

I wanted to know what are the theories and through what technology they plan to achieve it, nanotechnology,

genetics, biotechnology, and so on 

 

To be clear, the question is not how to extend life 

for example, extend life so we can live for more 100 years.

when i say cure i mean that if i dont get shot. i will live forever

 

 

I'm not native English speaker so...

 

[YOLF]

SENS.org is a great resource for information on this. 

 

To help ensure that you make it to the future, can also look at:

Alcor.org

Cryonics.org

OregonCryo.org

KrioRus.ru

 

Costs and options:

http://www.longecity...re-the-options/

 

Some other links:

Free Alcor Associate Membership:

http://www.longecity...ad-for-details/

Cryonics.org also has something similar.

Sustainable Health:

http://www.longecity...-in-a-nutshell/

 

[Mind]

I am pretty much on the SENS bandwagon for the first therapies that will repair the ravages of aging. There is good progress on the clearing of lipofuscin. Removing senescent cells looks promising as well, for the short term.

[bigbadwooof]

I have watched a couple speeches by a man names Aubrey de Grey, he is the Chief Science Officer for the SENS foundation... and he makes a lot of sense! XD

 

I like the general idea that the human body is 'a machine' that needs to be maintenanced, though I don't feel that it can be likened to 'maintaning a 100 year old car', as he puts it. A car is generally maintained by replacing parts as they go bad. I don't think that the intention of his research is to replace parts as they go bad, at least not generally speeking.

 

He does lay out a concise list of objectives, and I like that, although those objectives entail a lot more than they might lead one to think. Overall, I support his ideals and his approach, and I'm glad that they exist, and that they are making some level of progress. I am only 25 years old, so I may be fortunate enough to receive some of the benefits of his research, though it is likely that I will never be wealthy enough to afford such luxuries.

[alex172]

from what i understand from SENS.org.

their solution  is to repair the damages that  gathered, through biotechnology, right ?

By replacement of new tissues instead of damaged ones

 

what is the other ways ?

is ther other way through Nanotechnology ?

is ther other way through genetics?

 

i dont Support Cryonics. it is a good idea but not a Solution.

It does not extend life, it stops them to continue another time.

 

im 21. and instad of buying the technology to live how much i want, (Most likely not be able to afford)

i want yo study and Develop it instead.

 

i support Aubrey de Grey idea, but i doesn't...Connect(?) to it.

I'd rather find another solution that will Sounds better.

 

 

Correct me if I'm wrong.

[alex172]

Aubrey de Grey said that the human body is too complex to be interfered.

and everything is connected so if something in our body is being changed, is could cause unwanted reactions somewhere else.

 

in ather words, No one ever thought of using Human enhancement as away to Expand life ?

at least at most parts of the body there will be no tissue to be Damaged,

a situation wen the heart can stop without warning, will never happen

and after all it will be easy to to replace parts in a machine

Rather than replacing part in biological body

 

please tall me someone thought about it and start doing something

[bigbadwooof]

What do you mean by 'human enhancement' specifically?

[alex172]

by 'human enhancement' i mean machine parts. 

like the people without limbs, they use prosthesis.

same thing but without the real need for them.

 

it hard to me to explain

 

the best example of what i mean you can see here

http://deusex.wikia....concept_art.jpg

 

Unfortunately this is the only thing that shows the direction of what I mean

of course without all the nonsense of weapons and murder.

the Pure goal is extended lifetime

[bigbadwooof]

Ok, so pretty much what you're talking about is cyborgs... I think one of the best examples of this is the movie 'Repo Men' with Jude Law and Forest Whitaker...

 

I am actually more optimistic about lab generated organ transplants. In 2011 there was a man in Sweden whose trachea had been removed due to cancer. He had one grown in a lab from his own stem cells, and it was implanted into his neck successfully. It was the very first donor-less transplant. They took a 3D scan of his trachea, and used it to create a glass replica. Then they took stem cells from his bone marrow and covered the glass structure with them, and within 2 days they had formed a new trachea! Very cool stuff!

 

There's another new regenerative technology that is also fascinating. Columbia University is developing a method for people to re-grow their own teeth! It is likely to be cheaper to do than dental implants!

 

There are so many things going on these days. I see the aging process being attacked on a variety of fronts, and although the scientific climate in which anti-aging research exists could certainly be improved, it is quite awesome to see what is going on in the world. I watched a debate between Aubrey de Grey, and some Gerontologist the other day... And they were both arguing over semantics of defining what aging means and shit like that... but I think taking a new approach, such as de Grey suggests, is equally as important as continuing down the current path, by which we have actually come quite far. More funding all around would be nice! lol

 

The future is exciting, but even at 26 years old, I am doubtful that my lifespan will be significantly increased by science.

[alex172]

organ transplants is a nice idea. but what happen when the brain started to get damaged ?

plus the biological body is very vulnerable.

and transplants organ is to much dependent.

 

why do you doubtful obut increasing your lifespan?

[Vardarac]

 

and transplants organ is to much dependent.

 

I can't speak to brain rejuvenation and human augmentation (as interesting as I find the latter), but I can tell you that tissue engineering does not suffer from the same problems that mere organ transplantation does.

 

For one thing, scarcity and rejection will not be problems for engineered tissues. They are made from a combination of manufactured or naturally-derived materials onto which the patient's own cells are seeded and allowed to grow. As the artificial organ comes into maturity, it is planted into the patient as though it were any other organ that came from an animal or another patient.

 

If organ transplantation can be compared to changing motors between dissimilar cars, then tissue engineering might be seen as creating a functionally new motor for a car using its own parts. You don't have to wait for new organs (just the growth time for the patient's cells), nor do you face the problem of immunological rejection.

 

 

why do you doubtful obut increasing your lifespan?

 

I find anti-aging science fascinating and want it to work out, but there are major hurdles in the way of its success. Some of these problems are scientific, but some are social, as well - regulatory barriers, for one thing, and the possible collapse of the world financial and climate systems.

Edited by Vardarac, 04 May 2014 - 08:27 PM.

[alex172]

yes of course. that was the meaning, i didn't expect to live from donation from dead people.

anyway, tissue engineering is really seems to be a good idea to extend life.

but way not to extend life and make the human better, without doubt, with human augmentation?

be faster, be stronger, see better and be smarter.

without the fear that the heart can suddenly stop.

without the fear that a bullet or a knife can hit your heart.

without the fear that some Bacteria or Virus will mutate, develop resistance and start infect everyone.

 

and abut immunological rejection. of curse it a risk, but in my not professional opinion,

it will be very hard to get this effect if there will almost no biological tissue to reject something.

like in this picture

 

http://www.google.co...start=0&ndsp=15

 

and by the way, any problems that are not scientific.

any other problems are not Interesting and worth of my concern

of course there will be disadvantages. there always will.

 

at the end, all that i hoped is that someone will say something about human augmentation.

never mind, i want to develop this, or help develop this technology.

i just dont know were to start, and with What degree shuld i start.

i am 21 years old from israel, i just finished Serving in the army.

Almost certain to leave the country, fo canda maybe, i dont know.

and i open for suggestions and advices.

 

 

[Vardarac]

You're getting into transhumanist territory. I guess you could say that I'm sentimentally attached to my organic body, since I personally would want to augment rather than replace it; think the original Deus Ex instead of Human Revolution.

 

Right now, though, I think the main advantage to tissue engineering is that we are further in our understanding of it than we are of fully artificial human augmentations or replacements. Long life is not so much a bridge as a staircase made of a hodgepodge of different stairs. A series of improvements will have to be made rather than a single path.

[alex172]

what do you mean by transhumanist territory ?

[bigbadwooof]

Ok... I have to say, that I've read a lot of articles, and heard a lot of speeches about theoretical methods of life extension and augmentation and all of that. I find it fascinating.

However, Alex172, you have officially creeped me the fuck out with that picture. YUCK!

I would NEVER want to be that... thing...

I am with Vardarac on being attached to my body. There is more to what we are than just our brains. I like to feel my heart beating and my blood flowing. I like to feel alive!

[alex172]

i understand that it weird to think about the possibility of cutting and removing the biological body and remain with "nothing"

and i dont think that this possibility will make you feel less alive.

actually it look more efficient and logically achievable, in my opinion of course.

 

the way of tissue engineering is less good because it insured to live a life of surgeries

and dependent on the supplier of the tissue.

Additionally of the weaknesses of the human biological body that i mentioned before

 

there is another way that i know of that suggest to download the content of the brain to a computer and live a virtual life. it is very interesting way. because in that situation ther will be no need to worry about a body that can be hit or stop working.

 

but in my opinion, if i take a file(brain content) and copy it from A (biological brain) to

 B ( computer) . it is not a continuation of life. it is stopping  it in A, and restart it from B.

and giving the illusion of continuation.

 

if you know about another way that is better from augmentations by my way of thinking i will be glad to consider it as an option.

until then, augmentations will be my option.

and i really want to help to make that technology

i just need to choose a path that will help me get it.

nanotechnology, biotechnology, i dont know what i need and from what to start. 

i don't want to start something and after 4 years of study and getting a academic degree

to find out that it not really what will help me get my "dream"

 

[John Schloendorn]

You want to make an interface between biotech and human-made tech.  You need to know what can be known about both, and then figure out on your own how to interface them.  Humans are generally much better at human-made tech.  So if I were you I'd study bio as the main focus, and teach yourself tech on the side.  Because it's so much harder to do anything useful in bio than it is in tech.  

 

 

[YOLF]

 

by 'human enhancement' i mean machine parts. 

like the people without limbs, they use prosthesis.

same thing but without the real need for them.

 

it hard to me to explain

 

the best example of what i mean you can see here

http://deusex.wikia....concept_art.jpg

 

Unfortunately this is the only thing that shows the direction of what I mean

of course without all the nonsense of weapons and murder.

the Pure goal is extended lifetime

 

Cool trailers... but shouldn't smoking be banned in video games as it is on TV etc?

[ron45]

Forever? Really? It's bad enough with incumbent politicians. There are already too many people for the food production capabilities of the earth. I mean sustainable food production not the horror of amurikin agri-biddniss aszusual soil devistation. Consumers forever, shit factories for ever? What ever for? I can't get a way from that question.

 

We are already in the process of killing the planet, well on the way, If you want to live for ever move to another planet. What could you or myself offer this world that would justify all the perfectly good food we regularly turn into perfectly good shit? Which we use to pollute untold millions of gallons of water as pollutants instead of processing into useful compounds. 

 

Few people on this planet are worthy of eternal life. Why not be come a xtian or muzzelem, or jouuuuu, They offer eternal life if you kill for what's his name….. can't buy into that? Me neither. The only eternal life there is for us is Eternal Borborygmus in the ani of trillions of bacteria. That eternal enough for me and I don't have to by into someones control dogma. Ever wonder what kind of eternal omniscient allegedly devine being would tell his three waring sects of followers things to guarantee there participation in eternal war? I have. Religion is an intensionally inculcated device. Patriotism is an intentionally inculcated device. These two things…..excluding the biblical, toran, and what ever the muzzelem lie anthology is called…… also guarantee eternal war. If you ask yourself who would benefit from these intensionally brought about conditions……..the answers get more horrid the deeper you look. I'll tell you the secret to world peace and happiness. It's a bumper sticker that should  come installed on every vehicle 

 

To Hell with Cake. Eat the One percent.

 

Ron

[YOLF]

Well for one, we should have fertility on/off vaccines. There is nothing worse than creating a population where we cant optimally meet the socioemotional investment needs of everyone. The problems we have today and the fact that we accept this that some people are disposable justifies this. If we can procreate as well at 500 as we could at 20, why not? We'd be better parents able to take a family leave sabbatical until the kids are off on their own. This alone will slow the population growth to a manageable rate and allow us to make sure that we can end world poverty in short order. 

 

Aside from that, we should be leaving Earth as soon as we can. We're a terror to this planet with our bombs and reactors and it's better off without us. We should transition to living on orbitals. 

 

Sorry for the short response, but I do plan to do a series of blog posts on exactly this topic. Immortality (indefinite youth/healthspans) will be the best thing to happen to the human race since agriculture.