2 replies to this topic

[birthdaysuit]

Thanks!

[Area-1255]

Not that I know of. It's just a bonded mix of niacin and GABA.

 

Eksp Klin Farmakol. 2010 Jul;73(7):13-5.

[Effect of nootropes on quantitative changes in the rat cerebral cortex GABA(A) receptor complexes under experimental hypokinesia conditions].

[Article in Russian]

Akopian VP, Balian LS, Zakarian NA.

Abstract

The influence of picamilon and piracetam on the quantitative changes in the central GABA(A) macromolecular receptor complexes in the rat brain has been investigated under the experimental conditions of hypokinesia. It was found that the injection of these nootropes under the conditions of 7-day hypokinesia and 4-day recovery period did not show visible changes in the amount of active GABA(A) receptors. However, the injection of picamilon under the conditions of 15-day hypokinesia and 8-day recovery period showed a tendency to restoration of the number of active GABA(A) receptors.

PMID:   20821973   [PubMed - indexed for MEDLINE]

 

[gamesguru]

the conditions of 7-day hypokinesia and 4-day recovery period

Perhaps GABA^[1].

In case you throw that too far out of balance, there's always cow piss:

 

The isoflavones S-(–)-equol, 4′-hydroxy-7-methoxyisoflavone and 3′,7-dihydroxyisoflavone (Figure 2) isolated from bovine urine were found to displaced ³[H]-diazepam binding in rat brain

----------------

Some representative flavonoids that have been shown to influence benzodiazepine binding to brain membranes (30,7‐dihyroxyisoflavan, amentoflavone, apigenin, 6‐methy-lapigenin, and oroxylin A), to act at GABA_A as positive modulators (hispidulin) or negative modulators (amentoflavone, apigenin), or at GABA_C as negative modulators(apigenin). In addition, apigenin and ()‐epigallocatechin gallate have been found to have a novel second order modulatory action on the first order modulation of GABA_Aby diazepam.

Edited by gamesguru, 11 September 2015 - 09:43 PM.