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[JackieJackJackenstein]

It's a bizzare request, but I suffer heavily from intolerance towards certain ideas and behaviours. I speculate that this is due to my phenotype being that of the asshole from the prehistoric tribe that smashed the opposition's heads with a large bone.

 

Joking aside, does anyone know how to calm these feelings of intolerance? Of wanting to lord over everyone? Note that I've been under heavy stress for most of my life and have had a high pulse rate. Beta blockers seem to do the trick for me, but I'm afraid of developing tolerance to them. Right now I'm also some weeks into an antidepressant + mood stabilizer treatment.

[Agent0023]

I can identify with your complaint.  I started on beta-blockers in 1971 when propranolol was still an investigational drug and I was a war refugee jumping outta' my skin and occasionally quite explosive. 

 

Tolerance wasn't a problem, though at the maximum I was taking 4.5 grams a day (and fainting alot!).  I stabilized at about 160mg./day.   The problem was with missing a dose:  my pulse could go from ~45/m to 160/m within hours.  

 

Newer beta blockers with "intrinsic sympatheticomimetic effects" (ISA)  overcome this problem

 

The last blocker I've used was pindolol.   Worked fine for me.   For some reason calcium channel blockers really agree with with me temperamentally and mood wise.

 

Hang in there, they all take time to work.

 

 

 

Edited by Senolytic Agent 0023, 18 July 2016 - 03:34 AM.