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LongeCity .                       Advocacy & Research for Unlimited Lifespans

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CellAge: Targeting Senescent Cells w/ Synthetic Biology

crowdfunding lifespan.io fundraising advocacy matching matching funds cellage

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#61 LifespanKeith

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Posted 03 February 2017 - 04:20 AM

Not sure if the meme upload will work, but I thought it was fitting given the above comment ;)

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Edited by LifespanKeith, 03 February 2017 - 04:21 AM.

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#62 maxwatt

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Posted 03 February 2017 - 11:55 AM

HaHa.

 

You can read about the CellAge project here https://www.lifespan...thetic-biology/   

 

By targetting senescent cells, one can rejuvenate an organism:  such cells are not only non-functional, they release poisons that affect their neighbors, leading to many of the diseases of aging.

The CellAge project is developing substances that identify such cells in different cell types, enabling the development of treatments for specific maladies associated with aging.

 

Do contribute via the link on the pink bar at the bottom, below the thread so Longecity can match your contribution dollar for dollar.   If you want some of the swag Lifespan.io offers for contributions, Longecity will share your information.  For $25 you can have your name encoded in DNA.  Larger contributor prizes include ah hour video conference with Aubrey De Grey, or stay in a castle in Scotland...


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#63 caliban

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Posted 10 February 2017 - 12:18 AM

SUCCESS!

 

After yesterday's advertisement by lifespan.io and LongeCity, our sub-goal was quickly reached!

 

In fact, with the LongeCity support this means CellAge have now been able to reach their adjusted initial goal!  

 

Many warm thanks to all those who contributed to this brilliant result!  

 

 

Still in sight are the "stretch goals"  

 

$40,000:Stretch goal 1 – Assembly and screen After we have designed our senescent cell specific genetic circuits, our next goal will be to perform the actual DNA assembly, along with screening for functionality. This stage will require an additional $20,000 in funding for DNA synthesis, cloning and functionally testing our promoters in different cell types through the use of flow cytometry and microscopy. At the end of this stage, we will have our lead promoters identified.

→ source (external link)

 

Those wishing to contribute can do this at  ⇒ lifespan.io (we will of course forward all donations to this cause from here). 

 

 

 


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#64 meatball4u

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Posted 17 February 2017 - 01:49 PM

First I'm learning of senescence, following!

#65 maxwatt

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Posted 18 February 2017 - 03:07 AM

Look for topics on Rapamycin or Dasatinib. 



#66 caliban

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Posted 27 February 2017 - 10:16 AM

With the help of LongeCity, the many donors large and small and some external contributors not listed on the donors list, the overall fundraiser has now been closed with resounding success.

 

We will keep an eye on how the research progresses -with a particular interest in the LongeCity-sponsored sub-goal- and keep the community informed. 

 

This project has also been useful in considering potential broader collaborations between LongeCity and lifespan.io. This will be considered during our current Budget discussions. 

All Members are invited to offer feedback!

 

 


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#67 LifespanKeith

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Posted 27 February 2017 - 07:28 PM

Yes; thank you all for helping making this fundraiser a success. We are all definitely looking forward to see the progress on this project, and also to continue working with everyone here at LongeCity to bring more projects like this to the next level.

 

Thanks again everyone.


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#68 Steve H

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Posted 27 February 2017 - 09:21 PM

Many thanks to everyone at LC it really made a huge difference. I look foward to future collaboration with the community - we are all in this together :D







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