LONGECITY

Hi,
yes it has been a while since I wrote something here.  Here are two papers pusblished including the work funded by you:
Leovsky C, Fabian C, Naaldijk Y, Jäger C, Jang HJ, Böhme...
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As for the effect the transplanted microglia have on the pathology: I do not see a big difference in the amount of amyloid in the Alzheimer mouse brain without cells (A) and with microglia transpla... >

Hi again,
so we have started with our transplantations and some of our animals have been analysed. You see a picture showing our transplanted microglia in green and the amyloid in red. You ca... >

To visualize microglia and amyloid plaques in vivo, we established different staining protocols (including histology and immunohistology) to later evaluate microglia number after transplantation... >

We used several markers to prove that what looks like microglia really are microglia. We used so called surface markers (CDs) including CD11b and CD45. These markers are also used to distinguish be... >

To start with the microglia replacement therapy we need lots of cells and they must resemble the original microglia. In the pictures you see microglia isolated from mice (left) or self-made microgl... >

As a reminder WHY we are doing this:

What are microglia:

Microglia comprise about 10% of the cell population of the brain and form the main fi...
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In 2011, the Longecity community raised money to support a research project on microglia stem cell therapy.  Over the next few days, we will be reporting interim results in this blog.
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