Longecity seems to have a reputation for having smart people on here and so I turn to you to ask for help in figuring out what's wrong with my brain. I value your time so I'll try to be as brief as possible.
Problem: Low-ish mood (not persistent, comes and goes), irritability, lack of motivation, lack of interest in socializing (I want to be social but can't bring myself to care), and I find it challenging to stick with a task for a long time - I used to get very average grades in school, got easily bored in class and left homework for last minute and then did the bare minimum.
I've been evaluated by a psychiatrist who found mild social anxiety but I could've told him that and that's not something I'm concerned with right now. Family physician had me do a quiz on ADHD and depression and at best she said I could have low grade depression/dysthymia.
Things tried:
Ongoing: Weightlifting at least 3x a week, 2000 IU/daily vitamin D, meditation when I can bring myself to do it. Last annual physical came back clear.
20mg Paxil for about 9 months - first few weeks were great but my psychiatrist called it the honeymoon period. Felt very empathetic which is unlike me, social, and generally happy. That subsided and I was left feeling just content. Decided to go off it because of sexual side effects.
50mg Zoloft for a few months - can't say I noticed much of a difference except for sexual side effects.
2x600mg NAC - felt mood stabilizing effects but developed a bad case of heartburn which lasted for 3 or 4 days so I dropped it.
2x1600mg Piracetam - slight reduction in overall anxiety and a decent energy boost for a few hours after administration.
300mg KSM66 Ashwagandha (tried 2x300mg as well but a few weeks later I started noticing intermittent thyroid discomfort/pain so I lowered the dose to 300mg) - helps with stress and anxiety but nothing earth shattering.
250mg L-theanine with a cup of coffee - temporarily removes coffee jitters and lowers anxiety.
High dose EPA/DHA omega 3 - didn't notice any difference except for maybe a feeling of "brain fog".
3.5g Psilocybin trip - no profound effects, mainly just made me appreciate "sanity".
What to make of all this? I have a steady job, I exercise, but unless something dramatically changes I feel like I'll just coast through life never amounting to much. For the life of me I can't find the motivation to improve myself - to socialize, to read a lot, learn programming, etc.
I've attached genetic genie and nutrahacker results in case anyone's interested. Thank you for reading this wall of text!