.....I see it is available, but looks like a stimulant mostly. Anybody ever tried it? If so, what are the nootropic qualities?
L
onge
C
ity
Advocacy & Research for Unlimited Lifespans
Posted 15 September 2012 - 09:02 AM
Posted 15 September 2012 - 01:34 PM
Posted 15 September 2012 - 02:55 PM
Posted 15 September 2012 - 03:37 PM
Posted 15 September 2012 - 05:10 PM
Posted 15 September 2012 - 06:46 PM
Posted 15 September 2012 - 08:00 PM
Edited by @now, 15 September 2012 - 08:00 PM.
Posted 15 September 2012 - 08:34 PM
Posted 15 September 2012 - 08:46 PM
Posted 15 September 2012 - 09:23 PM
Posted 16 September 2012 - 10:41 PM
Posted 17 September 2012 - 08:08 AM
Posted 17 September 2012 - 08:59 AM
I would try to test fenotropil and ladasten "stand-alone". That way you'll know better what the benefits are. More importantly, you'll notice any side-effects much better.
Posted 17 September 2012 - 09:52 AM
Posted 17 September 2012 - 11:26 AM
Posted 22 September 2012 - 03:59 PM
Posted 22 September 2012 - 04:18 PM
Got some. Tried it. Basically a "boring" log: works as "advertised". Either there is a serious side effect - or it is very strange something like this isn't available in the west.
Details:
- took 50mg in the morning
- kicked in after 2h
- notably stimulating and anxiolitic
- better mood
- No noticable side effects
I think of it as anti-lethargy++ : you do all the little things without getting tired. No brain fog either. The difference compared to noopept is that you won't think "better" (but "more" - just better perserverance).
So if you're smart enough you'll get focus+++. I can also see how this will lift people out of a foggy/lethargic period: the stuff kicks in in 2h and lasts all day. Use that energy to change your habits and focus, keep at it some time, continue living without ladasten (my theory being that after a few weeks you get used to a different rythm)
I do think the dose of 50mg in the AM is enough given the half life of 11h AND you need to good care of yourself given that you'll burn more energy. Anyway, it definitely battles something that lot of people "fight".
Edited by Climactic, 22 September 2012 - 04:20 PM.
Posted 23 September 2012 - 05:07 AM
Got some. Tried it. Basically a "boring" log: works as "advertised". Either there is a serious side effect - or it is very strange something like this isn't available in the west.
Details:
- took 50mg in the morning
- kicked in after 2h
- notably stimulating and anxiolitic
- better mood
- No noticable side effects
I think of it as anti-lethargy++ : you do all the little things without getting tired. No brain fog either. The difference compared to noopept is that you won't think "better" (but "more" - just better perserverance).
So if you're smart enough you'll get focus+++. I can also see how this will lift people out of a foggy/lethargic period: the stuff kicks in in 2h and lasts all day. Use that energy to change your habits and focus, keep at it some time, continue living without ladasten (my theory being that after a few weeks you get used to a different rythm)
I do think the dose of 50mg in the AM is enough given the half life of 11h AND you need to good care of yourself given that you'll burn more energy. Anyway, it definitely battles something that lot of people "fight".
Posted 23 September 2012 - 07:25 PM
Edited by @now, 23 September 2012 - 07:26 PM.
Posted 23 September 2012 - 07:54 PM
Posted 23 September 2012 - 08:37 PM
Posted 23 September 2012 - 08:52 PM
Sorry, but it is not at all appropriate for you to scream "side effects" from an isolated experience, considering everything else going on in your life. This thread is starting to become post-heavy and content-free. How about we take it for a week or two, or over a period of time, and then post our experience? This isn't a chatroom.phenylpiracetam seems to have less side effects so far
Edited by Climactic, 23 September 2012 - 08:54 PM.
Posted 23 September 2012 - 09:25 PM
You guys don't understand that people will be reading these threads years from now, and they'll have to parse through all this junk. Do you see the user chrono post like this? Or do you see research papers come out in ten parts? No. All I am suggesting is - use your words and your posts carefully. Write as if you're writing a Study of One.^
Just to let you know: downvoted you and upvoted him.
Edited by Climactic, 23 September 2012 - 09:27 PM.
Posted 24 September 2012 - 01:22 AM
Posted 24 September 2012 - 02:19 AM
Posted 24 September 2012 - 05:37 AM
Posted 24 September 2012 - 05:52 AM
(also looking for a source of amisulpride, agomelatine, and phenylpiracetam)
Posted 24 September 2012 - 06:48 AM
Nootrabiolabs has lately been selling bulk phenylpiracetam on ebay. CoA here. It is cheaper than Phenotropil and Demiurge. I have yet to try it in 100-300 mg doses. I also have to subjectively compare its taste and potency with the other two.
Posted 24 September 2012 - 07:22 AM
Edited by @now, 24 September 2012 - 08:05 AM.
Posted 24 September 2012 - 10:13 PM
Derivatives of adamantane, like memantine, are potentially neuroprotective drugs for the favourable care of Alzheimer's and Parkinson's diseases. A further adamantane derivate is N-(2-adamantyl)-N-(para-bromophenyl)-amine (ladasten) which is capable to modulate animal performance in different learning paradigms. To clarify if some of those behavioural alterations are mediated by modulation of catecholamine syntheses we studied the effects of single administration of ladasten (50 mg/kg, per os) on catecholamines' biosynthesis in the ventral tegmental area, nucleus accumbens, hypothalamus, striatum and hippocampus. We found that ladasten differentially regulates tyrosine hydroxylase mRNA and protein as well as dopamine and L-DOPA content. We then investigated the effects of ladasten on activity-dependent hippocampal synaptic plasticity in vitro and found that application of 10 microM ladasten transforms short-term potentiation of synaptic transmission to a long-lasting form. A transformation of short-term into long-term potentiation was also observed, when ladasten was applied 40 min after a single 100 Hz 200 ms tetanization. This reinforcement was blocked by the protein synthesis inhibitor anisomycin and could be attenuated by the D1/D5 receptor antagonist SCH23390. These results suggest that ladasten induces reinforcement of short-term potentiation via protein synthesis and dopamine dependent mechanisms.
Edited by Tubemode, 24 September 2012 - 10:13 PM.
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