Well, to the best of my knowledge neurone development/growth (proliferation and differentiation) is modulated by opioids (mu and kappa respectively) so I immediately went to check what effect they have on glial cells, and it seems they proliferate them as well, in fact kappa opioids that normally differentiate and sometimes kill neurones seem to proliferate glial cells. This seems somewhat logical though since kappa signals for immediate survival and use(rather than mu for growth and investment) and glial cells are meant to help survival.
So I went to see if anyones used naltrexone(opioid antagonist) for glioblastoma and yes, studies are going on right now.
http://clinicaltrial...how/NCT01303835http://www.ldnscienc...cancer-patientsNow, the LDN benefits are being probably overhyped generally for all kinds of ailments, but in this case there might be reason for it to work.
Anyway, point is, to also research opioids as they are given as analgesics but are infact the primary modulator of neuronal stem cell growth and differentiation, so they might have side effects towards glial cells as well.
Naturally, the number one alternative option seems to still be cannabis oil. It is mentioned in that thread as well and I'm sure there's heaps of materials on it.
Another thing popped into my mind: ketogenic diet. Tumors feed on glucose and some are especially vulnerable to ketogenic diets. Ketogenic diet as a treatment is also bound to the brain - it is the only cure (meaning it can be ceased and the benefits remain) of epilepsy and efficacy is I think at 50% in children so there might be something more there. Ketogenic diet forces mitochondria energy production which I believe is misfunctioning in tumors (mitochondria I believe are responsible for inducing cell suicide before out of control replication begins?).
http://www.ncbi.nlm....pubmed/24442482http://www.google.hr....66111022,d.ZWUHope that helps :/
Edited by addx, 06 May 2014 - 07:23 PM.