Hi - sorting through the group buy thread is a task in itself, is anyone experimenting with Vorinostat and what is your experience? Thanks!
#1
Posted 22 January 2017 - 05:31 PM
#2
Posted 30 January 2017 - 09:29 PM
So I'd be combining exposure therapy with "meditation" in the form of a float tank session.
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#3
Posted 31 January 2017 - 05:05 AM
Keep us updated!
#4
Posted 01 February 2017 - 02:41 AM
would be interested to hear any experiences with sodium butyrate as well or even sodium valproate. i have a feeling its efficacy in bipolar disorder hinges on histone acetylation rather than gaba. hdac inhibition in the amygdala in particular is of interest as it determines anxiolysis of alcohol
#5
Posted 01 February 2017 - 02:54 AM
sodium valproate has had some success in social anxiety by increasing gaba inhibition in the cerebral cortex and its commonly thought that this is a separate effect from its hdac inhibition but as you can see sodium butyrate has a similar effect. https://www.ncbi.nlm...pubmed/26577018 leading me to believe gaba inhibition is a downstream effect of hdac inhibition.
Also tagged with one or more of these keywords: fear extinction
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