LONGECITY

She does look more youthful in recent photos. It's hard to believe she's (about) 48 years old. She looked young for her age even before receiving gene therapy.

Liz is almost 10 years older than me, but her skin kicks my skin's arse (If that makes any sense)!

I suspect that the telomerase treatment has helped her skin, given that skin turns over every month atleast. We know it's helped her immune system, atleast from the limited evidence of leukocyte telomere length. And I'd also expect to see improved gut barrier function.

Liz definitely needs to get some more useful biomarkers worked up.

Here's a picture from three years ago--https://i0.wp.com/ww...4x884.jpg?ssl=1

She looks early 30s in the above pic (2015) and late 20s in the most recent pic.

She looks early 30s in the above pic (2015) and late 20s in the most recent pic.

 

Additonally, the 2015 pic is a publicity shot, whereas the 2018 pic is only a facebook shot. So from this point of view it does appear Liz has gotten younger.

 

There is a discussion started by Liz on biomarkers here:

 

https://www.longecit...rs/#entry858996

Edited by QuestforLife, 27 September 2018 - 08:40 AM.

She looks great. You should come back for another QA Liz

 

 

http://www.youtube.c...h?v=f9YSzT_fOHI

Edited by marcobjj, 03 May 2019 - 08:39 PM.

I appreciate the effords done here towards rejuvination.

 

But my problem with judging her age from images and videos is the simple fact than women can look way different from simple makeup, nutrition or illumination. I would prefer much more standardized images (same light, same position, no makeup ) here.

 

 

 

I appreciate the effords done here towards rejuvination.

 

But my problem with judging her age from images and videos is the simple fact than women can look way different from simple makeup, nutrition or illumination. I would prefer much more standardized images (same light, same position, no makeup ) here.

 

 

In particular where the evidence of a product's efficacy is the face of the person marketing it.

In particular where the evidence of a product's efficacy is the face of the person marketing it.

Evidence? What's that?
 

Since when did longevity science get to be about evidence?

 

Well if I claimed to have a rejuvenation therapy, what better way of demonstrating that is there apart from walking around with amazing looking skin, hair, etc.?

Skin, after all is the largest organ in the body, and one of the most exposed to damage...

Only issue with Liz is that she looked pretty damn good to start with!

Well if I claimed to have a rejuvenation therapy, what better way of demonstrating that is there apart from walking around with amazing looking skin, hair, etc.?

Skin, after all is the largest organ in the body, and one of the most exposed to damage...

Only issue with Liz is that she looked pretty damn good to start with!

The largest organ in humans is the vascular endothelium. Unfortunately, she does not publish information about his condition.

And the skin can be easily smoothed in a huge number of ways.
Edited by Kentavr, 29 May 2019 - 04:32 PM.

And the skin can be easily smoothed in a huge number of ways.

Please do share. I can list a long line of supposed interventions for the skin that do not work...

Please do share. I can list a long line of supposed interventions for the skin that do not work...

 

For example:

"I met Ned David, I thought that he was about thirty. He had an unlined face and thick auburn hair, he walked rapidly with his hands stuffed into his jeans pockets, and he wore red Converse high-tops.

David is forty-nine. He is a biochemist and a co-founder of a Silicon Valley startup called Unity Biotechnology. Unity targets senescent cells—cells that, as they age, start producing a colorless, odorless, noxious goo called sasp, which Unity’s researchers call “the zombie toxin,” because it makes other cells senescent and spreads chronic inflammation throughout the body. In mice, Unity’s treatments delay cancer, prevent cardiac hypertrophy, and increase median life span by thirty-five per cent. “We think our drugs vaporize a third of human diseases in the developed world,” David told me.

David isn’t taking any of Unity’s drugs, which won’t be on the market for at least seven years. His youthfulness derives from existing therapies: he takes metformin—a diabetes drug that has made elderly diabetics live longer than a healthy control group—and Retin-A, for his skin. He also swims a lot, having quit running because of spinal osteoarthritis. “I am often accused, here, of picking the things we work on based on the problems of aging I have,” David said. “But because of our drugs I predict that I will run again!”

https://www.newyorke...to-live-forever

For example:
"I met Ned David, I thought that he was about thirty. He had an unlined face and thick auburn hair, he walked rapidly with his hands stuffed into his jeans pockets, and he wore red Converse high-tops.
David is forty-nine. He is a biochemist and a co-founder of a Silicon Valley startup called Unity Biotechnology. Unity targets senescent cells—cells that, as they age, start producing a colorless, odorless, noxious goo called sasp, which Unity’s researchers call “the zombie toxin,” because it makes other cells senescent and spreads chronic inflammation throughout the body. In mice, Unity’s treatments delay cancer, prevent cardiac hypertrophy, and increase median life span by thirty-five per cent. “We think our drugs vaporize a third of human diseases in the developed world,” David told me.
David isn’t taking any of Unity’s drugs, which won’t be on the market for at least seven years. His youthfulness derives from existing therapies: he takes metformin—a diabetes drug that has made elderly diabetics live longer than a healthy control group—and Retin-A, for his skin. He also swims a lot, having quit running because of spinal osteoarthritis. “I am often accused, here, of picking the things we work on based on the problems of aging I have,” David said. “But because of our drugs I predict that I will run again!”
https://www.newyorke...to-live-forever

He might just be one of those people who looks young naturally. Retin-A did nothing for me. Metformin doesn't affect skin other than indirectly through lowering blood glucose and mine is low anyway. Hyaluronic acid has a noticeable effect on the thin, sometimes crinkled skin on the back of hands, but does much less on the thicker skin of the face. Derma rollers can help with specific fine wrinkles but in the end they just form somewhere else (skin has to fold somewhere). Chemical peels can remove bumps but do nothing for wrinkles. The telomerase activators had no noticeable effect on my skin. Vitamin C (especially liposomal) and carnosine have beneficial effect on the skin, but nothing amazing. Red light might do something but I haven't tried it for long enough to eliminate placebo. I'm currently also trying out a statin skin cream of my own design, but hasn't been long enough to judge.

The above list might make you think I've got terribe skin. I haven't. I'm 40 and my skin is perhaps typical of someone on their mid to late thirties. But it seems very difficult to reverse skin aging. Even celebrities that 'look' young, when you look closely, you can see the age. Hence why I said skin is a great, real, biomarker for biological aging.

He might just be one of those people who looks young naturally. Retin-A did nothing for me. Metformin doesn't affect skin other than indirectly through lowering blood glucose and mine is low anyway. Hyaluronic acid has a noticeable effect on the thin, sometimes crinkled skin on the back of hands, but does much less on the thicker skin of the face. Derma rollers can help with specific fine wrinkles but in the end they just form somewhere else (skin has to fold somewhere). Chemical peels can remove bumps but do nothing for wrinkles. The telomerase activators had no noticeable effect on my skin. Vitamin C (especially liposomal) and carnosine have beneficial effect on the skin, but nothing amazing. Red light might do something but I haven't tried it for long enough to eliminate placebo. I'm currently also trying out a statin skin cream of my own design, but hasn't been long enough to judge.

The above list might make you think I've got terribe skin. I haven't. I'm 40 and my skin is perhaps typical of someone on their mid to late thirties. But it seems very difficult to reverse skin aging. Even celebrities that 'look' young, when you look closely, you can see the age. Hence why I said skin is a great, real, biomarker for biological aging.

Have you ever heard of cosmetics with peptides?

Have you ever heard of cosmetics with peptides?

That's something I haven't tried.