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What Increases CRH/ACTH/Cortisol?

crh acth cortisol

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#1 kurdishfella

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Posted 29 August 2018 - 10:43 PM


So I made a thread about what decreases CRH(Corticotropin-releasing hormone) & ACTH(Adrenocorticotropic hormone), so I thought why not make a thread about what increases them for people with low functioning cortisol?

 

here is what comes to mind(list is incomplete not 100% correct):

 

- Licorice 

- Serotonin & Dopamine / norepinephrine etc

- Hydrocortisone & prednisone

- Low Calorie Dieting Increases Cortisol

- Caffeine Stimulation of Cortisol Secretion

- don't sleep & finding ways of getting stressed out

- Cold showers.

- guarana+mate 600mg powder extract
- Most stimulants
- nicotine 

- Intense workouts

- Fasting / IF


Edited by farshad, 29 August 2018 - 10:46 PM.


#2 kurdishfella

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Posted 30 August 2018 - 11:28 PM

- marijuana

 

''exogenous cannabinoids have been shown to robustly affect the hypothalamic–pituitary–adrenal (HPA) axis causing increases in levels of corticotrophin-releasing hormone (CRH), adrenocorticotrophic hormone, and cortisol''

..''Stimulation of the HPA axis is believed to occur via brain cannabinoid receptor (CB-1R) activation primarily in the paraventricular nuclei of the hypothalamus where these receptors and CRH mRNA are co-expressed and also in the pituitary''


Edited by farshad, 30 August 2018 - 11:30 PM.


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#3 kurdishfella

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Posted 31 August 2018 - 03:44 PM

- Nardil

 

..''phenelzine significantly increased plasma ACTH and paraventricular hypothalamus CRH mRNA ''



#4 kurdishfella

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Posted 01 September 2018 - 02:15 PM

forskolin-stimulated CRH promoter activity

 



#5 kurdishfella

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Posted 06 September 2018 - 12:11 PM

Nicotine stimulates secretion of corticosterone via both CRH and AVP receptors



#6 kurdishfella

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Posted 14 September 2018 - 07:15 AM

''Naloxone, which increases endogenous corticotropin-releasing hormone (CRH) release by blocking an inhibitory opioidergic tone on the hypothalamic-pituitary-adrenal''


Edited by farshad, 14 September 2018 - 07:15 AM.


#7 kurdishfella

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Posted 15 September 2018 - 09:36 AM

''memantine alone at 20 mg kg(-1) (i.p.), but not 10 mg kg(-1), increased corticotropin-releasing factor (CRF) mRNA levels in the hypothalamus and both adrenocorticotropic hormone and corticosterone levels in the blood''



#8 kurdishfella

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Posted 22 October 2018 - 05:56 AM

Alcohol Dysregulates Corticotropin-Releasing-Hormone (CRH) Promoter Activity by Interfering with the Negative Glucocorticoid Response Element (nGRE)



#9 kurdishfella

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Posted 31 July 2019 - 07:18 AM

These results suggest that extrahypothalamic CRF1 receptors are involved in the effect of yohimbine on operant alcohol self-administration and on relapse to alcohol seeking and support the notion that CRF1 receptor antagonists should be considered in alcohol addiction treatment.



#10 kurdishfella

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Posted 07 August 2019 - 03:11 PM

Adrenocorticotropic Hormone (ACTH) Effects on Myelination in Subjects With MS
 
 
BDNF increases hypothalamus crh release which activates ACTH.
 
CRHR1 activation too.

Edited by farshad, 07 August 2019 - 03:11 PM.


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#11 kurdishfella

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Posted 03 August 2020 - 02:15 AM

Although both yohimbine and naloxone stimulated the HPA axis, only yohimbine appeared to have stimulatory effects on central NE and non-HPA CRH.

 

All these have effects on libido as well.







Also tagged with one or more of these keywords: crh, acth, cortisol

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