• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans

Photo
- - - - -

How can I upregulate 5HT2A legally?

5ht2a

  • Please log in to reply
5 replies to this topic
⌛⇒ write a quiz!

#1 neurobliss

  • Guest
  • 10 posts
  • 2
  • Location:USA

Posted 14 January 2019 - 06:52 PM


I have a sense of detachment, blunted affect, and loss of motivation/zest for life which I believe is due to decreased glutamatergic transmission. Modulating monoaminergic neurotransmitters doesn't seem to help with this issue. I have read an article about 5HT modulating glutamate signaling, and it was suggested in there that the safest way to modulate glutamate levels without risking excitotoxicity is via 5HT2A agonism.

 

Microdosing LSD or mushrooms is not an option for me because I have two small children and I can't risk a felony conviction, therefore I want to figure out how to this legally. Can anyone suggest legal/safe supplements or herbs that might get the job done?

 

https://www.ncbi.nlm...les/PMC2430669/

 

As the author suggested, the interplay between glutamate and 5-HT receptors offers new possibilities in the treatment of a glutamate deficit: as a matter of fact, the use of glutamate agonists would induce neurotoxicity and convulsions, whereas it might prove a good strategy to act on 5-HT2A receptors which in turn modulate glutamate-mediated effects [23].


Edited by neurobliss, 14 January 2019 - 06:58 PM.


#2 Rocket

  • Guest
  • 738 posts
  • 99
  • Location:Usa
  • NO

Posted 14 January 2019 - 08:04 PM

I think lisuride is what you're after.



sponsored ad

  • Advert
Click HERE to rent this advertising spot for SUPPLEMENTS (in thread) to support LongeCity (this will replace the google ad above).

#3 Galaxyshock

  • Guest
  • 1,169 posts
  • 153
  • Location:Finland

Posted 15 January 2019 - 08:33 AM

St. John's Wort upregulates 5-HT2A.

 

Panax ginseng is non-psychedelic 5-HT2A agonist.


  • Good Point x 1

#4 neurobliss

  • Topic Starter
  • Guest
  • 10 posts
  • 2
  • Location:USA

Posted 15 January 2019 - 01:33 PM

I think lisuride is what you're after.

It's not available in my country.



#5 neurobliss

  • Topic Starter
  • Guest
  • 10 posts
  • 2
  • Location:USA

Posted 15 January 2019 - 01:55 PM

St. John's Wort upregulates 5-HT2A.

 

Panax ginseng is non-psychedelic 5-HT2A agonist.

Thanks for the info! SJW doesn't seem to agree with me but I'm going to give P.ginseng a try.



sponsored ad

  • Advert
Click HERE to rent this advertising spot for SUPPLEMENTS (in thread) to support LongeCity (this will replace the google ad above).

#6 Rocket

  • Guest
  • 738 posts
  • 99
  • Location:Usa
  • NO

Posted 15 January 2019 - 03:10 PM

It's not available in my country.

 

You are in the USA. It is available as a research chemical. I have bought some for rat experimentation last year.







Also tagged with one or more of these keywords: 5ht2a

0 user(s) are reading this topic

0 members, 0 guests, 0 anonymous users