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Fisetin accelerates the rate of telomere shortening

fisetin telomere ampk

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#1 Yamu Xu

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Posted 07 May 2019 - 09:52 AM

I read a paper that said Fisetin accelerates the rate of telomere shortening:
Accelerated Aging during Chronic Oxidative Stress: A Role for PARP-1



AMPK activators can inhibit SASP, and AMPK and mTOR regulate autophagy too, what's more, activate AMPK can protect telomere!

So don't eat fisetin everyday, just eat some safe AMPK activators to control chronic inflammatory.


BTW, Alive by Nature's pills of activator contain fisetin, be careful of this.


What's more, H2O2 can increase NF-κb and NF-κb can cause chronic inflammatory too, so drinking H2O2 to activate AMPK is not a good idea,  we can eat some safe AMPK activators! I recommend baicalein as AMPK activator, baicalein has a strong effect of anti-cancer, and it can extended life span in  animal experiment, related paper:






Edited by Yamu Xu, 07 May 2019 - 09:53 AM.

#2 Yamu Xu

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Posted 07 May 2019 - 10:59 AM

extended life span→extend life span
Sorry for some spelling mistakes, English is not my first language.

Also tagged with one or more of these keywords: fisetin, telomere, ampk

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