1 reply to this topic

[opales]

Excellent papers, recommended for everyone interested in aging and life extension. 6 of papers support CR and 6 are against.

http://www.springerl...teposition=4#A4

Editorial:
http://www.springerl...lts,1:104841,1;

I especially enjoyed two critical views of which [1] is a must read for anyone claiming to be even vaguely interested in life extension (the paper applies couple of new theories on aging that could have wide ranging implications, even on the level of optimizing one's heath). [2] discusses the epidemiologies in Japan and their relevance to CR debate (+couple of other things).

[1]Braeckman BP, Demetrius L, Vanfleteren JR. The dietary restriction effect in C. elegans and humans: is the worm a one-millimeter human? Biogerontology. 2006 May 27; [Epub ahead of print]
PMID: 16732407 [PubMed - as supplied by publisher]

http://www.springerl...ults,1:104841,1

[2] Goto S. Health span extension by later-life caloric or dietary restriction: a view based on rodent studies.
Biogerontology. 2006 May 27; [Epub ahead of print]
PMID: 16732405 [PubMed - as supplied by publisher

http://www.springerl...lts,1:104841,1;

[Matt]

Thanks! Will print them out later to read...

Just reading quickly went through one of them and seen the following

(Vaupel et al. 1998). Assuming that the estimated
maximum life span potential noted above is the limit
of human life span, it is unlikely that the life span
increases further in human by CR/DR because the
average daily energy supply per person in Japan
(2761 kcal) has been 17% lower than the average
value of developed countries (3314 kcal), and 27%
less than that in the US (3774 kcal)

I thought the energy intake per person in japan was much lower than this. Many people doing CR intentionally (CRS) are far below intake, most around 1800 k/cal a day and some much lower.