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Shepard's Antiaging-Augmentation Regimen


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#1 Shepard

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Posted 07 June 2006 - 12:05 AM


All right, here is the ever-changing/evolving regimen that I do almost daily. I take weekend breaks from a few things, and if I'm going out to dinner, I won't usually take all my pills to keep people from thinking I have some horrible disease.

Upon awakening:
Enzymes.....................2 caps
Probiotics.....................2 caps
TMG..........................1 gram

1 hour before breakfast:
Inositol.......................1.5 grams
IP6.............................500mg
Glucuronolactone.........1 gram
NAC............................300mg (time release)
R+SR.....................1 cap
Vitamin C.................1 gram (time release ascorbic acid)
Hydergine……………..2.25mg

45 minutes before breakfast
Acetyl-L-Carnitine..........1 gram
Histidine........................2 grams
AAKG............................2 grams
Lysine...........................1 gram
Citrulline.......................3 grams

30 minutes before breakfast:
EGCG Max.............1 cap
Rhodiola................100 mg
Tyrosine................3 grams (with coffee)
SAMe....................400 mgs
LEF B-Complex......1 cap
Magnesium citrate……...400mg
Cordyceps................750mg
GTF Chromium…………..200mcg
Taurine.....................2 grams

With Breakfast:
Ortho-Core...................3 caps
RxOmega-3 Fish Oil.......2 grams
Vitamin C…………….1 gram (TR AA)
Now Bioflavonoids…...700 mg
Carnosine……………..500mg
Benfotiamine………….160mg
Pyridoxall……………..1 cap
AOR Total E…………..1 cap
Niacinamide…………...225mg
Lactoferrin……………..250mg
Methylcobalamin……….2mg
Cayenne…………………500mg
Turmeric…………………500mg
GSE/Resveratrol………….1 cap
Kyolic Garlic..............1 gram
Vinpocetine……………….15mg
Mushroom Optimizer………2 caps
Ginger……………………..500mg


1 hour before lunch:
Inositol.......................1.5 grams
IP6.............................500mg
Glucuronolactone.........1 gram
NAC............................300mg (time release)
R-Plus.....................1 cap
Vitamin C.....................1 gram (time release ascorbic acid)

30 minutes before lunch:
Green & White Tea...............1 cap
Rhodiola................................100 mg
Acetyl-L-Carnitine..................1 gram
Magnesium citrate..................400 mg
Taurine.................................2 grams

With Lunch:
Ortho-Core...................3 caps
Vitamin C…………….1 gram (TR AA)
Fish Oil.................2 grams
Cayenne…………………500mg
Turmeric…………………500mg
Astaxanthin……………….4mg
Pantethine…………..300mg
Kyolic Garlic..............1 gram
Mushroom Optimizer………2 caps
Ginger……………………..500mg
Benfotiamine………………80mg
Carnosine…………………..500mg
Pyridoxall..................1 cap

1 hour before dinner:
Inositol.......................1.5 grams
IP6.............................500mg
Glucuronolactone.........1 gram
R+SR…………………1 cap
NAC............................300mg (time release)
Vitamin C.....................1 gram (time release ascorbic acid)
TMG............................1 gram

45 minutes before dinner:
Propionyl-L-Carnitine…..1 gram

30 minutes before dinner:
SAMe...........................200mg
LEF B-Complex..............1 cap
Cordyceps.....................750mg
Magnesium citrate...........400mg
GTF Chromium…………..200mcg
Taurine.......................2 grams

15 minutes before dinner:
I3C.....................200mg

With Dinner:
Ortho-Core...................3 caps
Jarrow EPA/DHA Balance………….1 cap
Jarrow EPActive............1 cap
Vitamin C…………….1 gram (TR AA)
Now Bioflavonoids…...700 mg
Pantethine..............300mg
Carnosine……………..500mg
Benfotiamine………….160mg
Pyridoxall……………..1 cap
Lactoferrin……………..250mg
Cayenne…………………500mg
Turmeric…………………500mg
GSE/Resveratrol………….1 cap
Holy Basil…………………1 cap
Kyolic Garlic..............1 gram
Mushroom Optimizer………2 caps
Coenzyme Q10……………..100mg
Ginger……………………..500mg
Gingko Biloba…………….120mg
Cinnulin……………………125mg
Sesamin……………………..500mg

Before Bed:
R-Plus……………………..1 cap
L-Theanine………………..225-450mg
Magnesium Citrate………..200-400mg
Zinc………………………..30-45mg
Ashwaganda……………….1.5g
Bacopa……………………...300mg
Vitamin C....................2 grams (TR AA)
7-OH...........................50-100mg
Melatonin.....................3-5mg



Products used throughout the day (treated as supplements):

LEF Phyto Food
New Chapter Berry Green
Creatine…………5 grams
FOS……………..5 grams
Inulin……………5 grams
Pomegrenate concentrate………………2 Tbs
Cherry concentrate……………………..2 Tbs
Concord Grape Concentrate……………2 Tbs
Unsweetened Organic Tomato Sauce….2 Tbs
Olive Oil……………………………….1 Tbs
Apple Cider Vinegar……………………2 ounces
Lemon Juice (organic, fresh squeezed)…2 ounces
Cocoa Powder…………………………..10-15 grams
Organic coffee…………………………..1-2 cups
Organic green tea………………………..1-2 cups
Psyllium....................................10-20 grams
BCAAs......................................30 grams around workouts
Egg Protein................................20-40 grams (not ED)
Hemp Protein.............................15 grams (not ED)
Flax seeds……………………....1 Tbs



Products on hand (used when needed)

Deprenyl
Bromocriptine
Huperzine A
Pyritinol
Galantamine
Sulbutiamine
Piracetam
Aniracetam
Citicholine
Alpha-GPC
Centrophenoxine
Lecithin
Vincamine
N-Acetyl-L-Tyrosine
Various stimulants

Edited by shepard, 14 November 2006 - 12:13 AM.


#2 doug123

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Posted 07 June 2006 - 12:28 AM

Wow! Are you rich? What various stimulants are you using? No crystal meth I hope? :(

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#3 Shepard

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Posted 07 June 2006 - 12:37 AM

Wow!  Are you rich?  What various stimulants are you using?  No crystal meth I hope? :(


No, the various stimulants refer to stuff I use rarely in a crunch: ephedrine, caffeine, nicotine, Ergopharm Amp, etc.

#4 ajnast4r

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Posted 07 June 2006 - 08:15 PM

wow... thats quite the regimen.

whats that costing you? 500, 600$ a month?

hopefully ur putting as much money & effort into your food?

#5 kenj

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Posted 07 June 2006 - 09:46 PM

I see a Paul Wakfer getting PWNED badly here... [lol]

While I'd assume you have done a search or two on all of this you should keep in mind many of these substances in higher doses (noting Arginine, Glutamine, caffeine, Carnosine dependent on genetic factors) may elevate your histamine leading to allergic reactions (sympathetic responses) in the long run -- which 20000+mg :) Quercetin would NOT be able to handle.
I definitely wouldn't mix all this with any semi-harder substances, not even occasionally.

I would be curious how you handle all these pills? Do you organize this in a small container divided in daily servings?

#6 DukeNukem

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Posted 07 June 2006 - 09:54 PM

Not too far from what I do Shepard, though I'm not nearly as regimented with regard to what time I day I take my stuff. I take about 110 pills daily, a morning batch, a small afternoon batch, and an evening batch. Plus, I add a bunch of supplements to my morning oatmeal.

What is Glucuronolactone?

#7 ajnast4r

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Posted 07 June 2006 - 10:07 PM

Not too far from what I do Shepard, though I'm not nearly as regimented with regard to what time I day I take my stuff.  I take about 110 pills daily, a morning batch, a small afternoon batch, and an evening batch.  Plus, I add a bunch of supplements to my morning oatmeal.

What is Glucuronolactone?


http://en.wikipedia....lucuronolactone

#8 Shepard

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Posted 07 June 2006 - 11:50 PM

hopefully ur putting as much money & effort into your food?


Maybe I should add in diet, and what I wash my hair with, etc. Just like old times.

But, diet is good. I don't say that I restrict any foods (in that, at some point of the year, I'll probably have some of everything). But what I would consider unhealthy meals are kept low...1-2 month...more if I am forced to eat out a lot.

#9 Shepard

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Posted 07 June 2006 - 11:51 PM

I would be curious how you handle all these pills? Do you organize this in a small container divided in daily servings?


I have a scary-good memory. I just walk into my closet when it's pill time and get to popping.

#10 zoolander

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Posted 07 June 2006 - 11:51 PM

Awesome regime shepard.

I would consider taking the melatonin before bed.

Have you considered

1. Galantamine (have a read of Synthesis and Pharmacology of Galantamine)
-I have had some great results with galatamine. beware of the nausea though. I recommend that you do some reading first
-I recently recommended galantamine to a friend. Positive result for them as well

Edited by zoolander, 09 June 2006 - 12:54 AM.


#11 opales

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Posted 08 June 2006 - 09:10 AM

Maybe I should add in diet, and what I wash my hair with, etc. Just like old times.


You don't happen to own & run any nootropic companies we should probably be aware of? [lol]

#12 Centurion

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Posted 08 June 2006 - 01:16 PM

Shep man, what the?!??!?!?!
Are you rich or something? I can understand Duke Nukem taking that amount of stuff, CEO salary and all that...

#13 FunkOdyssey

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Posted 08 June 2006 - 02:25 PM

Shep, what do you think of MR's position on supplementation with highly-unsaturated fatty acids? DHA is exceptionally vulnerable to peroxidation, and he notes that mitochondrial inner membraine "peridoxizability" is inversely associated with maximum lifespan. Feeding rodents DHA increases the DHA content of their mitochondrial membranes. Also supporting the idea, CR reduces "peridoxizability" of these membranes by reducing their highly-unsaturated fatty acid (in particular, DHA) content. CR reduces desaturase activity in humans.

From a health standpoint, he argues that the cardiovascular benefits can be obtained with ALA, and that no benefit results from consuming more than 1-2 servings of fish a week anyway.

His original notes with links to references can be found here: http://www.cron-web....ts-guide-5.html

From my own knowledge of the subject, DHA has not been shown to do much of anything useful in adults that was not later attributed to the EPA content of the fish oil. We also know that the human body, when provided with ALA, will convert a much larger proportion of it to EPA rather than DHA (5:1 or 5:2)

#14 sentrysnipe

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Posted 08 June 2006 - 02:46 PM

Probably a son of an oil tycoon :D
Now if I could only obtain all these stuff. I'm thinking of applying for a loan.

#15 Shepard

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Posted 08 June 2006 - 04:21 PM

Shep, what do you think of MR's position on supplementation with highly-unsaturated fatty acids?  DHA is exceptionally vulnerable to peroxidation, and he notes that mitochondrial inner membraine "peridoxizability" is inversely associated with maximum lifespan.  Feeding rodents DHA increases the DHA content of their mitochondrial membranes.  Also supporting the idea, CR reduces "peridoxizability" of these membranes by reducing their highly-unsaturated fatty acid (in particular, DHA) content.  CR reduces desaturase activity in humans.

From a health standpoint, he argues that the cardiovascular benefits can be obtained with ALA, and that no benefit results from consuming more than 1-2 servings of fish a week anyway.

His original notes with links to references can be found here: http://www.cron-web....ts-guide-5.html

From my own knowledge of the subject, DHA has not been shown to do much of anything useful in adults that was not later attributed to the EPA content of the fish oil.  We also know that the human body, when provided with ALA, will convert a much larger proportion of it to EPA rather than DHA (5:1 or 5:2)


I've found MR's argument to be very interesting. I haven't quite made up my mind, yet. Two things hold me off from swapping to an EPA dominant fish oil (or just swapping to flax): the mountain of evidence for fish oil in the traditional ratios, and some evidence I read a long time ago regarding EPA vs. DHA and the beneficial aspects of DHA on the cardiovascular system (and with it, the insulin sensitivity effects). There was also mention of DHA being needed to convert to EPA in times of stress, but I haven't delved into that enough to form an opinion on it. If I'm wrong and haven't kept up with the newest research regarding EPA vs. DHA and the cardiovascular system, please let me know. I'll go back over Michael's arguments and see if he references the studies that I saw before, I'll also try to dig those up.

I also thought someone was going to post their own regimen. Now I'm all alone and left hangin'.

#16 FunkOdyssey

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Posted 08 June 2006 - 04:32 PM

Alright, hang in there for a few more min. [tung]

#17 xanadu

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Posted 08 June 2006 - 05:46 PM

Buy in bulk and cap it up yourself. Save a bundle. Or pay 5x as much or more for the same thing.

#18 Shepard

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Posted 08 June 2006 - 05:49 PM

It's a mixture. I buy some in bulk, and some others I don't. It depends on the particular item.

#19 FunkOdyssey

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Posted 08 June 2006 - 10:08 PM

Whats your source for Pyridoxall? Whats your reasoning for using a single dose of 125mg of cinnulin PF at dinnertime? Your thread here reminded me that I wanted to take extra chromium -- thanks!

#20 Shepard

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Posted 08 June 2006 - 10:39 PM

I use the cinnulin at dinnertime due to decreased insulin sensitivity later in the day, and usually add a little more carbs to my dinner meal (due to exercise schedule).

Pyridoxall is still sold at www.vitaminlady.com

#21 Shepard

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Posted 09 June 2006 - 12:49 AM

After some deliberation, I'm cutting my supplement regimen a little...by approximately $85 or so a month. I haven't quite decided what is getting cut yet, and I'll post up when I do. Opinions are welcome, too.

#22 opales

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Posted 10 June 2006 - 05:20 PM

After some deliberation, I'm cutting my supplement regimen a little...by approximately $85 or so a month. I haven't quite decided what is getting cut yet, and I'll post up when I do. Opinions are welcome, too.


Just noticed your new sig, it appears that the $85 you save by cutting back on supps is being well spent elsewhere. Welcome aboard [thumb]

#23 ajnast4r

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Posted 10 June 2006 - 07:32 PM

if it was me, i would cut:

Di-Arginine-Malate
L-Lysine
L-Ornithine
Glucuronolactone
K-RALA
Coenzyme Q10
Dim
Garlic

#24 stellar

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Posted 11 June 2006 - 12:37 AM

I take about 110 pills daily


Holy $h1t!

#25 doug123

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Posted 11 June 2006 - 12:40 AM

After some deliberation, I'm cutting my supplement regimen a little...by approximately $85 or so a month. I haven't quite decided what is getting cut yet, and I'll post up when I do. Opinions are welcome, too.


Just noticed your new sig, it appears that the $85 you save by cutting back on supps is being well spent elsewhere. Welcome aboard [thumb]


It seems I am all talk with my Mprize love. I got to step up to par with Shepard. I'll do it with the first shirt. Hold me to my word, opales; I know you will! Peace.

#26 scottl

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Posted 11 June 2006 - 08:07 PM

From a health standpoint, he argues that the cardiovascular benefits can be obtained with ALA, and that no benefit results from consuming more than 1-2 servings of fish a week anyway.


1. If you take flax, you need to take GLA..I suppose I should post this as a seperate topic and explain.

2. It is a crapshoot hoping the body will convert enough ALA into ePA. There are lots of things that interfere, and if you look at the studies you see varied rates probably for several reasons. How do you know which rate your body is?

3. Fish contains both. See this article....doesn't really prove anything...still a hint...

http://www.imminst.o...025&hl=miner&s=

#27 ajnast4r

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Posted 11 June 2006 - 08:41 PM

1. If you take flax, you need to take GLA..I suppose I should post this as a seperate topic and explain.


why is that? i know the same enzyme is responsible, but unless your taking 30-40g ALA... i dont see how there would be a problem

2. It is a crapshoot hoping the body will convert enough ALA into ePA.  There are lots of things that interfere, and if you look at the studies you see varied rates probably for several reasons.  How do you know which rate your body is?



as long as you are not nutritionally deficiant & not consuming an excess of omega6... then there should be no problem converting. all the studies ive read are flawed in that: 1) there is no monitoring of the factors that contribute to decreased conversion (as mentioned above), and 2) that conversion is a very long process, something like 120hours to peak. to get from ALA to EPA takes a few days. to get a real idea of conversion rates you would have to administer flax for a few days, and check a week later.

#28 scottl

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Posted 11 June 2006 - 09:15 PM

1. the same enzyme is responsible,

and prefers the flax. what are you basing:

"unless your taking 30-40g ALA".

on?

1 tablespoon=15 g. 2 tablespoons=30 grams not an unreasonable dose.

2. "as long as you are not nutritionally deficiant & not consuming an excess of omega6... then there should be no problem converting."

Based on?

The studies are all over the place and like many conversions there is variability. Fine the studies are biased. So there is no data then to back up what you say (or is there?). DOn't forget also not everyone eats as healthy diet as you.

I believe there are other confounding factors e.g. sat fat, trans fats...B vit deficiencies perhaps others (? mineral)

Bottom line if I take EPA (or EPA/DHA) I know what I am getting. You cannot know how much you are getting.

Also this is one thing if one is 30 and taking it for prevention, and more vital if one needs or wants larger doses which ain't a bad idea to prevent inflammation, hearet disease, lower triglycerides, etc.

Edited by scottl, 11 June 2006 - 09:26 PM.


#29 ajnast4r

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Posted 12 June 2006 - 12:24 AM

1. the same enzyme is responsible,

and prefers the flax.  what are you basing:

"unless your taking 30-40g ALA".

on?


guessing the amount of ALA it would take to throw off the normall 3/6 ratio people usually consume. just a guesstimate


1 tablespoon=15 g.  2 tablespoons=30 grams not an unreasonable dose.


1 tablespoon = 12g total fat... only 8g ALA

so thats 4 tablespoons if flax per day to reach 30 grams ALA... people only usually consume 1-2 tbsp


2. "as long as you are not nutritionally deficiant & not consuming an excess of omega6... then there should be no problem converting."

Based on?


based on the factors that inhibit the conversion to begin with.

The studies are all over the place and like many conversions there is variability.  Fine the studies are biased.  So there is no data then to back up what you say (or is there?).  DOn't forget also not everyone eats as healthy diet as you. 


no data, but i have a good working knowledge of the process... so i think i can make some safe asumptions. the fish oil companies give low conversion numbers, the flax oil companies give high conversion numbers... so if you use a number right in the middle, the conversion is still more than adaquate.

i know most peoples diets arent great... but i would imagine most here are pretty close to mine.

I believe there are other confounding factors e.g. sat fat, trans fats...B vit deficiencies perhaps others (? mineral)


yup, trans fat, b, zinc, a few other things i forget off the top of my head.

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#30 scottl

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Posted 17 June 2006 - 05:34 PM

Shepard,

where do these come from?

Pomegrenate concentrate………………2 Tbs
Cherry concentrate……………………..2 Tbs
Concord Grape Concentrate……………2 Tbs




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