• Log in with Facebook Log in with Twitter Log In with Google      Sign In    
  • Create Account
  LongeCity
              Advocacy & Research for Unlimited Lifespans
  • .org
  • Districts
  • Media
  • SupportUs
  • Collaborate
  • Contact
  • Search
  • Join

Photo

CD38 gets in the way of NR and NMN for increasing NAD+

Started by Michael Lustgarten , Feb 02 2021 10:49 AM
cd38 nad+ nmn aging longevity

  • Please log in to reply
2 replies to this topic

#1 Michael Lustgarten

  • Location:Boston
  • NO

Posted 02 February 2021 - 10:49 AM


NR and NMN are popular ways to try to boost levels of NAD+, but that approach hasn't worked every time in human studies. One reason for that may involve CD38, which degrades both NR and NMN. With the goal of boosting NAD+ levels during aging, why does CD38 increase with age, and what can be done about it?


  • Informative x 2
  • like x 2

#2 Mind

  • Life Member, Director, Moderator, Treasurer
  • 19,898 posts
  • 2,000 ₮
  • Location:Wausau, WI
  • ✔

Posted 02 February 2021 - 04:50 PM

Interesting connection with LPS and endotoxins. Thanks for sharing.


  • Good Point x 1
Click HERE to rent this GENETICS advertising spot to support LongeCity (this will replace the google ad above).

#3 Heisok

  • Guest
  • 615 posts
  • 203 ₮
  • Location:U.S.
  • NO

Posted 02 February 2021 - 10:01 PM

There have been other threads discussing CD38 inhibition. Hopefully some more great information will also be shared in this thread.

 

Links to two of several:

 

https://www.longecit...ne/#entry847892

 

https://www.longecit...-consumer-cd38/


Edited by Heisok, 02 February 2021 - 10:01 PM.

  • Good Point x 1
Back to Biomarkers & Genes



Also tagged with one or more of these keywords: cd38, nad+, nmn, aging, longevity

1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users

  1. LONGECITY
  2. → Science & Health
  3. → AgingResearch
  4. → Biomarkers & Genes
  5. site rules