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Generation and Characterization of Anti-Glucosepane Antibodies Enabling Direct Detection of Glucosepane in Retinal Tissu

glucosepane

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#1 Major Question

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Posted 06 April 2021 - 03:19 AM


(Not sure if this is the right place to post this. If not, let me know.)

 

Generation and Characterization of Anti-Glucosepane Antibodies Enabling Direct Detection of Glucosepane in Retinal Tissue

 

https://pubs.acs.org...chembio.0c00093

 

Has anyone heard about this recent research? Antibodies being used against glucosepane. David Spiegel is among those involved. Sounds like a notable step towards this area of aging research.

 

"Here, we report the development of the first polyclonal anti-glucosepane antibodies using a synthetic immunogen that contains the core bicyclic ring structure of glucosepane."

 

"We believe that the anti-glucosepane antibodies described in this study will prove highly useful for examining the role of glycation in human health and disease."


Edited by Major Question, 06 April 2021 - 03:22 AM.






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