High FGF21, Low Insulin And Glucose: A Pro...
Michael Lustgarten
30 May 2021
https://www.youtube....h?v=NreBsyaj0l0
Papers referenced in the video:
FGF21 and Chronic Kidney Disease: https://www.scienced....com/science...
The starvation hormone, fibroblast growth factor-21, extends lifespan in mice: https://www.ncbi.nlm...gov/pmc/arti...
Inhibition of growth hormone signaling by the fasting-induced hormone FGF21: https://pubmed.ncbi....ih.gov/18585...
Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice: https://pubmed.ncbi....ih.gov/32877...
Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression: https://pubmed.ncbi....ih.gov/31773...
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice: https://www.ncbi.nlm...gov/pmc/arti...
Regulation of longevity by FGF21: Interaction between energy metabolism and stress responses: https://pubmed.ncbi....ih.gov/28552...
Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging: https://pubmed.ncbi....ih.gov/33131...
Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue: https://pubmed.ncbi....ih.gov/30043...
Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individuals: https://pubmed.ncbi....ih.gov/26042...
Lower All-Cause, Cardiovascular, and Cancer Mortality in Centenarians' Offspring: https://pubmed.ncbi....ih.gov/15571...
Favorable Glucose Tolerance and Lower Prevalence of Metabolic Syndrome in Offspring without Diabetes Mellitus of Nonagenarian Siblings: The Leiden Longevity Study: https://pubmed.ncbi....ih.gov/20398...
Edited by Michael Lustgarten, 30 May 2021 - 10:35 AM.
