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Apparently Senescence is not Irreversible

senescence rejuvenation senolytics

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#1 sensei

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Posted 03 February 2022 - 12:45 AM


"Inhibition of 3-phosphoinositide-dependent protein kinase 1 (PDK1) can revert cellular senescence in human dermal fibroblasts"

https://pubmed.ncbi....h.gov/33229519/


Of interest is MTORC1 inhibition also inhibits PDK1/PDPK1 (same thing 2 acronyms)
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Also tagged with one or more of these keywords: senescence, rejuvenation, senolytics

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