2 replies to this topic

[StephCThomp]

Has anyone used a senolytic protocol to help their pet dog to live long and well?  How did it go?

 

Which substances did you use, and at what dose?

 

Any recommendations or cautions?

 

Thanks.

[pepsseeker618]

been down this rabbit hole for my old dog — from what i found there's basically zero canine data, it's all mouse studies so dosing is a total guess. my vet was ok with quercetin on its own since it actually gets used in dogs for allergies, but wanted nothing to do with the stronger senolytic combos. honestly keeping him lean and active has done more than anything i've read about fisetin so far

[Mind]

I used fisetin for my cats. I dosed 4 of them (one was the cat of an acquaintence). All of them showed subjective improvement in energy/vitality. I was unable to determine any benefits through biomarker measurements. One of the cats was 23 years old. He hadn't been doing much for 6 months. Just sleeping and eating cheese. After the fisetin treatment, he started roaming around the house again and jumping up on the bed. He only lived for three weeks though, so not sure if the fisetin was overall beneficial or had some sort-of negative side effects. Only one of the cats that was dosed is still alive, 14.5 years old and doing well (got the fisetin treatment at 10 years old and again at 11 years old). The other two cats were old and died 6 months to a year after the fisetin treatment. They showed subjective improvements in energy/vitality, but again no objective measurements were taken.