Most research papers I find on amphetamines are bigly biased.
- Older set of research: views it as an evil toxic monster, citing doses that obviously will be toxic/bad for health.
- Newer set of research is superficial, views it as one of best nirvana treatments for attention deficit, citing therapeutic doses, and closing the topic.
There is this huge "stigma". I feel, what ties both these groups together is there lack of depth, a disdain for inquiry, as both these groups stick themselves to level of: Dopamine, Norepinephrine, re-uptake inhibition, brain specific neuro-coritcal bla bla, same dumb stuff over and over. Clearly d-amphetamine has pronounced systemic effects related to motility, gastric, muscle, cell energy, etc.
Now, I do have iron-clad will power, I would never succumb to addiction. And I find d-amphetamine (but not the l-amphetamine isomer) as one of the most potent anti-aging drug when "micro-dozed". All the above can be ignored, most important of all - my frustration: I do not find a single study that discusses it at a molecular level, data in context of ATP, mTOR, AMPK, NAD+, Mitochondria/OxPhos, Glycolysis, Cell cycle, epigenetics, aging, etc etc. Against or For - I do not care, I am not here to get validated or sit in an echo-chamber. Now I do acknowledge my searching skills are abysmal, and I get easily blindsided so help me here please. Is there one single soul on earth, that knows this topic?
Edited by Learner056, 14 September 2022 - 07:36 PM.
