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How long to stay on/off Rapamycin to not inhibit mTOR2?

rapamycin mtor1 mtor2

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#1 LiveWellLiveLong

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Posted 29 May 2023 - 08:37 PM


The benefit of preventative Rapamycin therapy seems to be inhibition of mTOR1, but side effects and negative effects can come when one simultaneously inhibits mTOR2 by staying on Rapamycin too long.  Does anyone have any research for how long to stay on Rapamycin before mTOR2 becomes downregulated?  Also, how long should one stay cycled off Rapamycin before getting back on it so that one could only downregulate mTOR1 and not mTOR2?


Edited by LiveWellLiveLong, 29 May 2023 - 08:38 PM.






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