66 replies to this topic

[DukeNukem]

These are supps I consider off the beaten track for most supplement users, or supps that may not have solid proven benefits but I take anyway because the risk is very low versus the potential benefits. Just so people are clear, I'm not a heavy researcher or pubmed junkie like a lot of people here -- I get most of my information from second-hand sources/experts, and I think I've developed a good sense for spotting credible sources. Plus, I never rely on one expert source (unless there's a super solid study backing the source), I tend to rely on corroborating sources to give me a level of comfort.

I tend to jump on promising supplements early if the risk seems very low, which is what I did with cocoa, pomegranate, resveratrol and many other food-based supplements that, IMO, had very little downside other than cost. When the supplement is more risky (mostly xenobiotics or noots), such as alagebrium chloride, I tend to do a lot deeper personal research and also wait to see the reactions of early adopters.

Not all of the following supplements have superstar benefits (though some do), but I'm convinced they all have a worthwhile benefit, and/or no significant downside.

o acarbose (Glucobay) -- taken with food, reduces sugar absorption
http://www.antiaging...2z/acarbose.htm

o alagebrium chloride -- undoes certain glycated bonds
http://morelife.org/...ms/ALT-711.html
contact: kitty@morelife.org if interested

o aminoguanidine -- reduces glycation damage
http://www.antiaging...noguanidine.htm
http://morelife.org/...archems/AG.html

o Arimidex -- an aromatase inhibitor, to boost testosterone levels
http://www.drugs.com/arimidex.htmlOral
(I use this through the guidance of my longevity doctor.)

o DPA Gold -- seal oil, containing a rare omega-3
http://www.thewolfec...l/seal-oil.html
This next link, though, seems to dispute DPA benefits:
http://holfordwatch....a-and-seal-oil/
It's worth noting that DPA is found in mother's milk, which convinces me that it's not harmful.

o d-ribose -- boosts ATP (adenosine triphosphate) levels, providing cellular energy
http://www.lef.org/n.../item00972.html
http://search.lef.or...x...SE dribose

o EUK-189 (generic) -- superoxide dismutase/catalase mimetics
http://morelife.org/...ms/EUK-189.html
contact: kitty@morelife.org if interested

o lactoferrin -- a nontoxic immune enhancer and iron binding molecule
http://www.advance-h...actoferrin.html
http://au.health.yah...tml?r=967673105

o Lyprinol -- an inhibitor of the 5-lipoxygenase pathway (anti-inflammatory)
http://www.lyprinol.com/
http://www.physician...p;name=Lyprinol

o NtBHA -- supplement for mitochondrial health
http://morelife.org/...hems/NtBHA.html
contact: kitty@morelife.org if interested

I take several other exotic supps -- maybe a new list next year.

Edited by DukeNukem, 31 December 2007 - 10:17 PM.

[MP11]

I take several other exotic supps -- maybe a new list next year.

I hope by next year you mean tomorrow.

[sUper GeNius]

I'd be more interested in your top ten, not your bottom ten. But thanks anyway.

Edited by shepard, 31 December 2007 - 11:15 PM.
Removed long quote.

[DukeNukem]

We don't need another top ten list from me. That's why I put a new spin on my yearly list. Also, several of these are really important to my program, and not part of a "bottom ten" list -- five especially I would qualify as must-take supplements. Exotic does not equate to unimportant.

BTW, you'll get a lot more respect around here paying as a full member, rather than naming yourself as one, clever as that may be.

[sUper GeNius]

We don't need another top ten list from me. That's why I put a new spin on my yearly list. Also, several of these are really important to my program, and not part of a "bottom ten" list -- five especially I would qualify as must-take supplements. Exotic does not equate to unimportant.

BTW, you'll get a lot more respect around here paying as a full member, rather than naming yourself as one, clever as that may be.

How's this. You provide me the link to a top ten list post of yours you posted previously, (you imply you've done that several times,) and I'll pay my genuine Full Member dues. Deal?

[Shepard]

How's this. You provide me the link to a top ten list post of yours you posted previously, (you imply you've done that several times,) and I'll pay my genuine Full Member dues. Deal?

http://www.imminst.o...o...c=13532&hl=

The first person that says "The question was 10, not 12" is getting banned.

[nushu]

Duke, did you take T levels before and after starting Arimidex? Have you been able to maintain higher levels?

[sUper GeNius]

How's this. You provide me the link to a top ten list post of yours you posted previously, (you imply you've done that several times,) and I'll pay my genuine Full Member dues. Deal?

http://www.imminst.o...o...c=13532&hl=

The first person that says "The question was 10, not 12" is getting banned.

Well, I was hoping for a link from Mr. Nukem, (since I asked him a couple of times in the past,) but in the spirit of the holidays, I will honor my pledge. In a few minutes...

[maxwatt]

How's this. You provide me the link to a top ten list post of yours you posted previously, (you imply you've done that several times,) and I'll pay my genuine Full Member dues. Deal?

http://www.imminst.o...o...c=13532&hl=

The first person that says "The question was 10, not 12" is getting banned.

Hey, 12 for the price of ten! What a deal!!

Edited by maxwatt, 01 January 2008 - 12:42 AM.

[DukeNukem]

I could have sworn I did a list for 2006, too, but can't find it -- must not have posted it here, and just sent it around to friends. I did find this very mid-2005 post by me, a mini-list, where I mention cocoa and resveratrol in the thread:
http://www.imminst.o...;hl=supplements

Anyway, glad that you're becoming a full member, Full Member. ;-)

[Ghostrider]

I could have sworn I did a list for 2006, too, but can't find it -- must not have posted it here, and just sent it around to friends. I did find this very mid-2005 post by me, a mini-list, where I mention cocoa and resveratrol in the thread:
http://www.imminst.o...;hl=supplements

Anyway, glad that you're becoming a full member, Full Member. ;-)

Hey Duke, I am pretty sure I remember reading your 2006 list as well...

[sUper GeNius]

I could have sworn I did a list for 2006, too, but can't find it -- must not have posted it here, and just sent it around to friends. I did find this very mid-2005 post by me, a mini-list, where I mention cocoa and resveratrol in the thread:
http://www.imminst.o...;hl=supplements

Anyway, glad that you're becoming a full member, Full Member. ;-)

Done. I feel younger already!

[EmbraceUnity]

I was originally interested in D-ribose for exercising purposes because of the impressive mice studies I saw through the LEF, but I researched more and most seemed to think it was useless. What's the story?

Edited by progressive, 01 January 2008 - 02:33 AM.

[ajnast4r]

=
o DPA Gold -- seal oil, containing a rare omega-3
http://www.thewolfec...l/seal-oil.html
This next link, though, seems to dispute DPA benefits:
http://holfordwatch....a-and-seal-oil/
It's worth noting that DPA is found in mother's milk, which convinces me that it's not harmful.

seal oil? ... PUKE
thats f'n disgusting..

why not drink kitten oil.. or virgins blood...

jesus christ

[luminous]

=
o DPA Gold -- seal oil, containing a rare omega-3
http://www.thewolfec...l/seal-oil.html
This next link, though, seems to dispute DPA benefits:
http://holfordwatch....a-and-seal-oil/
It's worth noting that DPA is found in mother's milk, which convinces me that it's not harmful.

seal oil? ... PUKE
thats f'n disgusting..

why not drink kitten oil.. or virgins blood...

jesus christ

Well, people seem to accept fish oil, including myself. Granted, a fish is not a mammal. Still, that brings to mind...how, exactly, is fish oil acquired?

Nevermind, I don't want to know.

[ajnast4r]

Well, people seem to accept fish oil, including myself. Granted, a fish is not a mammal. Still, that brings to mind...how, exactly, is fish oil acquired?

Nevermind, I don't want to know.

i'll leave my vegetarian rants somewhere else... but come on.. SEAL OIL? thats just rediculous

if you can look at urself in the mirror in the morning after eating part of one of these, then by all means drink it up man...

Edited by ajnast4r, 01 January 2008 - 04:47 AM.

[tintinet]

Well, people seem to accept fish oil, including myself. Granted, a fish is not a mammal. Still, that brings to mind...how, exactly, is fish oil acquired?

Nevermind, I don't want to know.

i'll leave my vegetarian rants somewhere else... but come on.. SEAL OIL? thats just rediculous

if you can look at urself in the mirror in the morning after eating part of one of these, then by all means drink it up man...

Agreed- a bit on the blood of the innocent side, and yet, "spray dried plasma" in protein supplements freaks me out even more!

Edited by Michael, 19 March 2011 - 11:48 AM.
Remove image - redundant, speed load time

[luminous]

Well, people seem to accept fish oil, including myself. Granted, a fish is not a mammal. Still, that brings to mind...how, exactly, is fish oil acquired?

Nevermind, I don't want to know.

i'll leave my vegetarian rants somewhere else... but come on.. SEAL OIL? thats just rediculous

if you can look at urself in the mirror in the morning after eating part of one of these, then by all means drink it up man...

I wasn't making a case for seal oil, really. However, do you (or others) consider fish somehow less worthy than seals, perhaps because fish aren't quite as cute? Just wondering.

I'm not a vegetarian, but I've come close in the past. I just can't get past certain things. I do hate the thought of eating other animals, but I like my shoes and handbags to be made out of leather. I guess I'm selfish. My thought is that if you're truly a vegetarian for ethical reasons, then you probably shouldn't be eating fish or wearing leather. Eggs would have to be ruled out as well, unless you know for sure that your egg came from a happy chicken who was allowed to live outside and wander freely. Oh, and milk (and cheese), too, same reason (substitute "milk" and "cow" for "egg" and "chicken"). So for me, I'd have to be a vegan to call myself a true vegetarian.

I am SOOO off topic, I think the thread police are coming after me. Maybe a special allowance could be made since it's new year's eve?

Alternatively, I could get back on topic:

Duke, those ARE exotic supplements. Have you noticed any benefits from them, particularly seal oil?

(edited to remove a repeated picture of the seal...not that I don't think he's cute :-)

Edited by luminous, 01 January 2008 - 05:18 AM.

[ajnast4r]

I wasn't making a case for seal oil, really. However, do you (or others) consider fish somehow less worthy than seals, perhaps because fish aren't quite as cute? Just wondering.

I'm not a vegetarian, but I've come close in the past. I just can't get past certain things. I do hate the thought of eating other animals, but I like my shoes and handbags to be made out of leather. I guess I'm selfish. My thought is that if you're truly a vegetarian for ethical reasons, then you probably shouldn't be eating fish or wearing leather. Eggs would have to be ruled out as well, unless you know for sure that your egg came from a happy chicken who was allowed to live outside and wander freely. Oh, and milk (and cheese), too, same reason (substitute "milk" and "cow" for "egg" and "chicken"). So for me, I'd have to be a vegan to call myself a true vegetarian.

i personally consider no animal less or more worthy than another, and actually am a vegetarian.. dont wear leather, make sure my eggs come from from cruelty free farms, etc etc :p


i think the cute-ness factor comes into play, you wouldnt catch most meat-eaters having kitten strew or puppy burgers...
as well as the fact that it is a highly conscious and socially complex animal...

its just so wrong!

widdle baybee seal!

Edited by Michael, 19 March 2011 - 11:52 AM.
trim quotes

[sdxl]

Since when are research chemicals and Rx drugs supplements?

[DukeNukem]

With regard to seal oil, I'm an animal lover and would never hurt any without very good reason (such as SENS progress). I researched the seal oil situation and what I learned is that in Canada seals must be thinned out yearly just the same as deer in certain areas of the USA. This is where the seal oil is acquired, all under government regulation. In other words, there's not a black market for this stuff where masked men at night are clubbing these animals just for the purpose of getting their oil for supplements.

As for my perceived benefits of DPA, I don't have any -- but I can say the same for practically all the supps I take. This one falls into the very low risk bucket, so the only downside is cost.

Edited by DukeNukem, 01 January 2008 - 05:05 PM.

[DukeNukem]

>>> Since when are research chemicals and Rx drugs supplements?

What would you prefer to call them?

Many people here, including me, also supplement with Deprynel and Metformin. Even though these are Rx drugs, they can also be life extension/health improving supps.

Edited by DukeNukem, 01 January 2008 - 05:08 PM.

[unbreakable]

>>> Since when are research chemicals and Rx drugs supplements?

What would you prefer to call them?

Research chemicals and prescription drugs.

Many people here, including me, also supplement with Deprynel and Metformin. Even though these are Rx drugs, they can also be life extension/health improving supps

I also think Selegiline and Metformin are useful agents, but I wouldn't call them "supplements".

Edited by unbreakable, 01 January 2008 - 05:12 PM.

[balance]

A search on pubmed also gave me results saying D-ribose was useless.. I don't know what to believe on it..

Excellent list though Duke. You think a 20 year old could try these supplements?

[DukeNukem]

>>> A search on pubmed also gave me results saying D-ribose was useless.. I don't know what to believe on it.

At your age, I wouldn't worry about d-ribose in the least. This is definitely one of those supps that the jury is still out on, and besides, even it is works as LEF suggests it does, it's more beneficial for people 40+.

>>> You think a 20 year old could try these supplements?

If money were not a factor, then these supps would very likely benefit you: alagebrium chloride, aminoguanidine, NtBHA.

[krillin]

A search on pubmed also gave me results saying D-ribose was useless.. I don't know what to believe on it..

My impression is that it's good for people with mitochondrial problems or heart failure, but not useful as a preventative.

[trance]

With regard to seal oil, I'm an animal lover and would never hurt any without very good reason (such as SENS progress). I researched the seal oil situation and what I learned is that in Canada seals must be thinned out yearly just the same as deer in certain areas of the USA. This is where the seal oil is acquired, all under government regulation. In other words, there's not a black market for this stuff where masked men at night are clubbing these animals just for the purpose of getting their oil for supplements.

As for my perceived benefits of DPA, I don't have any -- but I can say the same for practically all the supps I take. This one falls into the very low risk bucket, so the only downside is cost.

Does your source actually ship seal oil capsules to the US? I tried other places in the past, but my order was later refused since it was a US address ...

[DukeNukem]

With regard to seal oil, I'm an animal lover and would never hurt any without very good reason (such as SENS progress). I researched the seal oil situation and what I learned is that in Canada seals must be thinned out yearly just the same as deer in certain areas of the USA. This is where the seal oil is acquired, all under government regulation. In other words, there's not a black market for this stuff where masked men at night are clubbing these animals just for the purpose of getting their oil for supplements.

As for my perceived benefits of DPA, I don't have any -- but I can say the same for practically all the supps I take. This one falls into the very low risk bucket, so the only downside is cost.

Does your source actually ship seal oil capsules to the US? I tried other places in the past, but my order was later refused since it was a US address ...

My source refused initially, until I talked him into it. I think what he did was have a friend send me the package, so that, if discovered, it could not be tracked back to him. I made a large order to make this extra effort worthwhile.

[maxwatt]

I wasn't making a case for seal oil, really. However, do you (or others) consider fish somehow less worthy than seals, perhaps because fish aren't quite as cute? Just wondering.

I'm not a vegetarian, but I've come close in the past. I just can't get past certain things. I do hate the thought of eating other animals, but I like my shoes and handbags to be made out of leather. I guess I'm selfish. My thought is that if you're truly a vegetarian for ethical reasons, then you probably shouldn't be eating fish or wearing leather. Eggs would have to be ruled out as well, unless you know for sure that your egg came from a happy chicken who was allowed to live outside and wander freely. Oh, and milk (and cheese), too, same reason (substitute "milk" and "cow" for "egg" and "chicken"). So for me, I'd have to be a vegan to call myself a true vegetarian.

I am SOOO off topic, I think the thread police are coming after me. Maybe a special allowance could be made since it's new year's eve?

Alternatively, I could get back on topic:

Duke, those ARE exotic supplements. Have you noticed any benefits from them, particularly seal oil?

i personally consider no animal less or more worthy than another, and actually am a vegetarian.. dont wear leather, make sure my eggs come from from cruelty free farms, etc etc


i think the cute-ness factor comes into play, you wouldnt catch most meat-eaters having kitten strew or puppy burgers...
as well as the fact that it is a highly conscious and socially complex animal...

its just so wrong!

widdle baybee seal!

There is a dilemma for those of us who would be vegetarian. EPA is necessary for cellular health, Either we get it from an exogenous source, or our bodies synthesize it from shorter-chain omega-3 oils, such as flax. To synthesize it we need delta-5 desaturase. As we age, we produce less delta-5 desaturase, and exogenous EPA is needed to maintain optimum levels. Unfortunately, there are no vegetarian sources of EPA (or DHA, or DHP -- these are related long-chain omega-3's, they are approximately interchangeable, but are post-delta 5 products.) In short, there is no satisfactory vegetarian source of these essebtial long chain omega-3 oils. Flax is not a substitute.

Clubbing baby seals to death to press oil out of their broken bodies does seem kind of gross. More so than gettng it from fish.