5 replies to this topic

[VictorBjoerk]

TTR-amyloidosis seems to be a common cause of death among supercentanarians.What is this actually and how is it possible to prevent it?How does it affect the body making the systems shut down?

Many autopsied supercentenarians seem to have died directly or indirectly from it.I speculate Madame Calment ccould have died of it too.

[VictorBjoerk]

Well,does anyone know anything about it?

[inawe]

Well,does anyone know anything about it?

I asked Ms. Wiki Pedia and here is what she said:
ATTR, Transthyretin = A mutant form of a normal serum protein that is deposited in the
genetically determined familial amyloid polyneuropathies. TTR is also
deposited in the heart in senile systemic amyloidosis.

[niner]

Well,does anyone know anything about it?

Resveratrol might help prevent TTR-amyloidosis: http://pmid.us/10742177

[inawe]

Well,does anyone know anything about it?

Resveratrol might help prevent TTR-amyloidosis: http://pmid.us/10742177

Yes. Resveratrol and catechin gallate seem to be somewhat effective
"against Ass-induced toxicity" (PMID: 17406978).

[VictorBjoerk]

interesting, Does anybody know if it is somehow possible to repair the damage of it? As far as I understand most old people would have some damage due to different kinds of amyloidosis when getting to a certain age regardless of family heritage.

How it is connected to the aging process,is it a inevitable pathology when reaching advanced age?