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Testosterone


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43 replies to this topic

#31 VictorBjoerk

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Posted 05 May 2008 - 11:35 PM

Those that become centenarians really do generally look far younger than their age at most or all points of time in their life. Sure we can't say much on lifespan in regards to just how young someone looks, but nevertheless this is still a consistent thing seen among CR'd rodents, rhesus monkeys, dogs, and also seems to be true in humans (those on long term CR). And sure we can assume that a minority of models/super models are on some sort of CR that is healthy.

I think some calorie restrictors look younger than their age


Yes, quite a few of those on long term CR really do seem to be aging slowly, both biologically [Fontana studies] and 'I think' look younger than their chronological age.


Interesting channel.One should think of the fact that even though a long-term practioner may have less general age-related pathologies wrinkles and such things is more visible and people usually associate very thin people with disease regardless of their otherwise health status.
Have you met Michael Rae in peson?

#32 rhodan

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Posted 08 May 2008 - 08:42 AM

Dude must be crazy short.

In his blood analysis spreadsheet, his height is 175 cm, which is not short.

I cannot find anything recent on Dean Pomerleau (his website is out-of-date), wonder if he is still on his CR regimen ?

#33 Matt

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Posted 08 May 2008 - 01:02 PM

Dude must be crazy short.

In his blood analysis spreadsheet, his height is 175 cm, which is not short.

I cannot find anything recent on Dean Pomerleau (his website is out-of-date), wonder if he is still on his CR regimen ?


He doesn't post on the CR lists anymore, not since 2006 I think. No idea if he is on CR but you could just email him I guess. Lately he's getting some fame for his intelligent fish lol

#34 VictorBjoerk

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Posted 10 May 2008 - 11:52 PM

1998 calories a day sounded quite much for someone of Dean's height and weight....

#35 Guest_Kismet_*

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Posted 29 May 2008 - 04:17 PM

Not as long as the influence of sport, BMR and other factors on CR is unknown.
As I have already mentioned in another thread, I don't think any study examined, whether changing caloric balance by mainly restricting food or increasing exercise calorie expenditure is equivalent.

#36 Alpha-Frequency

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Posted 01 June 2008 - 03:17 PM

I can say with full certainty that when I am at a higher weight, I look and act as if I am 20 years older. What I notice about CR is that you tend to "feel" younger.

#37 Luna

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Posted 24 June 2008 - 07:33 AM

As far as I understand a severe calorie restriction diet would reduce testosterone and then of course cause loss of body as well as facial hair.


Why? For example, women with PCOS often get facial hair. Do you think the hormonal profile of a man on CR is similar to a woman with PCOS?


If you have low testosterone beard growth and body hair will reduce.If the defiency continues for many years it will disappear comletely.I don't understand your question.

I wonder why someone who has had a confirmed very low testosterone level for a long time due to CR still keeps the male hair pattern.

Any suggestions to why?


Are you certain that if you have a low testosterone for years, the facial hair will disappear completely? can you show any information on that, as I remember seeing it just slows down but never stops.

And isn't the male baldness pattern DHT related and not T? (isn't that same on facial hair?)

#38 Prometheus

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Posted 24 June 2008 - 01:18 PM

Another thing I don't understand when talking about low testosterone.Why do adult men with low testosterone experience fatigue as well as depression and general poor health?Children doesn't suffer from that kind of things and apparently not the cr humans with low testosterone.


Or women. Good point. Anyone care to have a go at answering this?

#39 VictorBjoerk

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Posted 24 June 2008 - 03:19 PM

Yes if you don't have testosterone you will keep your hair on your head and lose it on your body if the defiency is severe enough for a long time.

Or women. Good point. Anyone care to have a go at answering this?



Yes I've been wondering this for a long time.I know there are people here with the knowledge to answer this,and no I can't find it using google.

Winterbreeze: you can google or search nejm or whatever and i'm sure you will find some evidence for it. However you will still continue to have vellus hair of course.... But terminal beard and body hair will diminish gradually and disappear completely within a couple of years......
Male baldness can't occur in someone with genes for it if they don't have DHT which normal testosterone-filled men have plenty of.

#40 HaloTeK

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Posted 02 August 2008 - 03:13 AM

Nice Topic! This is probably a good place to introduce my hypothesis that there could be a difference between living vigorously and living long. Ever notice how many of the longest lived people on the earth are short (and usually thin). This connection almost certainly has to do with hormones. What influences hormones the most? Genetics and diet. Take someone who lives on a protein-rich paleo diet. Almost certainly, he will have an abundance of testosterone and good body composition (because the promotion of growth-type hormones). His resistance to disease and ability to recover are almost certainly very high for many types of injury. Let us contrast that with someone who is on a CR-type diet. His absolute protein intake will almost certainly be less than that of the paleo group. Also, almost all levels of growth type hormones, testosterone, DHT, DHEA, growth hormone, insulin etc. would be less. Resistance to disease is heightened because of some hormetic-like function on cells because of the reduction in caloric intake.

Debates rage on for the perfect range of protein, fat, carbs, but even with some genetic optimizations, there is going to be some type of ratio that promotes the most longevity. And there will be a trade off for body composition! Want to have muscles, sex drive, and so on? You might not live as long (how much is the question), but you can always hold out for genetic cures.

The main question is -- what is the real difference in longevity from someone who is really doing all they can to increase longevity. Once again, I see a lot of the paleo types looking really good and muscular even into there 80s, but what happens once they hit 90+, hmmm. Some of them list keeping insisting that keeping insulin as low as possible (on protein rich, high fat, low carb diet) is the best way to longevity. There is just no way this is possible on a diet that might keep insulin low, but other growth type hormones sky high! (think about how SHBG drops on a high fat diet!) Not to mention we don't know everything about the effect of certain macronutrients on cell turnover (like protein) <--- akin to what is happening when are DNA is replicating, but not perfectly. Some of the reason why the high carb diets around the world have been associated with longevity may be because of the anaerobic metabolism they may partially promote (once again, this may be hormetic) - where a high fat diet might be partially detrimental because of the oxygen-rich environment it promotes.

Now, if someone told you that you'd live only 2-5 years longer (thats probably what we are looking at with non-genetic interventions) on a diet that makes you look weak would you really do it? When you could be looking really strong and vibrant (the choice is really up to you).

And if you have any doubt that a lower amount of growth hormones is beneficial for longevity. Just look to the exceptionally long-lived. Every year they live they lower the amount of growth-type hormones they produce (and this is helping them live even longer! --- think about the difference between his testosterone production at age 30 compared to 100). Just think about what a farce HRT might look like in the future (in terms of sacrificing long term health for looks).

Seems to be that you want a diet that lowers all types of growth hormones to the lowest levels. We need to analyze what ratio of protein/fats/carbs this would be. After knowing what causes the greatest longevity without detriment, we can then tweak the ratios for adding muscle growth for those that want a little more without sacrificing much overall longevity (and dont want to look like a twig)-. Then, we can hold out for gentic therapies!

Sorry if this contains some bad english!

#41 VictorBjoerk

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Posted 02 August 2008 - 09:38 AM

so you think it is unhealthy to give old people growth hormone.

#42 doordonot

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Posted 05 October 2008 - 02:35 PM

i say so what, my Grandmother lived to be 106 and did not follow any special diet or even lifestyle, the only thing she continued to do was work everyday and leave a crack in the window at night when she slept. She also had a cup of brandy every night as well and she ate alot of candy. I would vow that genetics have a huge influence on our life span because her son who is an avid alcoholic is 87 now, and is still very active. It doesnt make sense how they dont even care yet some calorie restricters would make life so hard on themselves when someone who is drinking and smoking lives longer anyway.

#43 wydell

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Posted 05 October 2008 - 03:31 PM

i say so what, my Grandmother lived to be 106 and did not follow any special diet or even lifestyle, the only thing she continued to do was work everyday and leave a crack in the window at night when she slept. She also had a cup of brandy every night as well and she ate alot of candy. I would vow that genetics have a huge influence on our life span because her son who is an avid alcoholic is 87 now, and is still very active. It doesnt make sense how they dont even care yet some calorie restricters would make life so hard on themselves when someone who is drinking and smoking lives longer anyway.


My belief is also that genetics is a dominant factor, but that lifestlye does have an effect on how you look, your health, and longevity. That's pretty clear. You can see that lifestlye has an effect through studies.

Some random thoughts:

Perhaps though folks with great genetics and unhealthy lifestlyes would have even better health, longevity, and appearance, if they took better care of themselves. Or maybe they would just miserable without candy, alcohol and cigarettes, and that misery would cause them to be stressed out and they would have shorter lives. Who knows?

While many CRers will have live shorter lives than your relatives, perhaps they are getting an extra 10 years on their lifespan through their practice . And maybe it's not hard for them and perhaps they enjoy calorie restriction.

#44 doordonot

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Posted 06 October 2008 - 03:04 AM

my grandmother was very active, which would tie into lifestyle, and she hardly ever seemed stressed, she just always seemed content, no matter what happened. IMO, the less someone worries, the better off they are, so, yes, if calorie restriction is what makes you feel good, and you really enjoy it, and its not putting too much stress and worry into your life, than thats great.




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