It's my belief that we are going to find that overall, any hormone boosted state will bring about a decline is maximal longevity.
Think Jeanne Calment (122, 4'11).
Think Asian Cultures (usually shorter than other groups, high SHBG from higher carb diets, more androgynous looking (less hormones), overall good longevity).
Yes, this may be correct in many cases, but only for now as long as there is this nasty problem of fast growth (cell division) -> faster senesence and/or cancer. However, your theory does not apply to all - or rather most - hormones, because not all of them regulate growth or "androgenity". Many hormones are most benefical at the highest quartile of intake/blood levels (e.g. vitamin d/calcitriol, generally speaking androgens), whereas growth hormones seem to be rather detrimental at higher levels. Much more depends on the hormone signalling involved and most hormones require some trade-offs even at their optimal level. High testosterone is associated with a longer lifespan AFAIK (but correlation does not imply causation) and will certainly prevent falls, osteoporosis and sarcopenia at least to some degree, but it will probably increases the likelihood of prostate cancer.
An interesting paper:
Hormonal regulation of longevity in mammals
http://www.pubmedcen...978093#id376737
Edited by kismet, 04 January 2009 - 10:06 PM.