sunburn peelies suggest a way of doing immortality research a way of finding chemicals that slow aging
Given that UV causes peelies why is it that the depthfully penetrating UV rays only cause a few micrometer layer of tissue to die You might predict a deeper volume response if it was UV generated free radicals rather than a preprogrammed apoptosis trigger
the wider effect of radiation causing death amongst dividing dermatocytes is likely a different effect as these are hundreds of cytes away from the layer that actually peels off
that gives a couple hypothesis: UV radiation does not kill tissue It causes tissue to rapidly operate its lifecycle faster with the more aged outer layer being rushed along as the entire cytostack structure increments an aging program also they hypothesis that UV causes a near field apoptosis trigger just upstream from a particular aspect of vital cytofunction
If that is the case then new medications that affect the production of peelies from mild UV dosages are testable
Beyond sunscreen topically applied radiation resistance chemicals can be tested on whole organism aging I have written previously about a molecule I found at medline It was a US study of a melatonin molecule with a lengthy /\/\/\/ hydrocarbon link If I remember right This compound gives seven times greater radioprotection from gamma radiation Note: that is seven times the survival at a particular dose
anyway if you measure a wide library of UV peely reducing chemicals as to effect then test them on entire organism longevity new immortality drugs may be found
There is variation Topical acetylsalicylic acid as well as ibuprofen gives numerous SPF reducing peelies yet these block nflammation cascades yet have only mild longevity effects
I just thought that imminsters might like trying various new compounds to reduce UV peelies different than sunscreens
CeO linked to melatonin The Lanthanides La Ce Pr Nd generally You could, if you were Truly risk friendly blend picture tube phosphor coatings with dmso to see if they reduced UV damage This fantastically bizarre mildly dangerous research strategy would give you data on the lanthanides Ce Eu Gd Terbium as well as Yttrium http://www.geocities...t_phosphors.htm There is a CeO radical longevity study as well as http://www.ncbi.nlm....Pubmed_RVDocSum
amifostine
perhaps thiosulfate compounds
mitotic ac well as meiotic active chemicals
Edited by treonsverdery, 15 July 2009 - 06:40 PM.
