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Sulbutiamine


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#1 mxr808

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Posted 06 March 2010 - 12:20 PM


Today my order of Sulbutiamine (Arcalion) arrived and after having taken 400mg and a further top up of 200mg I must say I'm quite impressed with the effects. The wakefulness and mental alertness is amazing and instantly noticeable so I'm really hoping I can use this nootropic in my times of need.

I just wanted to ask a few questions for people who have experience with this.

Do you respond to it?

At what dosage do you respond enough so there is a pronounced effect?

Do you take a choline source with it?

What effects do you experience?

How long does it take for your tolerance to build up?

Thanks.

#2 nito

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Posted 06 March 2010 - 04:37 PM

Can you tell us where you bought it please?
cheers

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#3 mxr808

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Posted 06 March 2010 - 04:46 PM

Can you tell us where you bought it please?
cheers


My supplier was:

http://www.unitedpha...?productid=1006

Except I used the UK version of the site. At first I was sceptical due to the amount of counterfeit prescriptions you can find online. The reason I ended up using it is because I'm based in the UK where Sulbutiamine is prescription only. I believe they're based in Oceania. The packaging seems genuine. Proper seal and has a batch number. Manufactured by Serdia Pharmaceuticals in India under license by Servier, France. Received 60 x 200mg tablets. The actual processing of the order took around 2 days which was a bit long but delivery only took 9 business days so was happy with that.

Even though it's only my first day of trying it the effects are so pronounced that I've pretty much made my mind up about adopting it permanently. I feel so invigorated and energized. I am in the best mood I've had in a long time.

#4 nito

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Posted 07 March 2010 - 12:14 AM

I'm uk based too. What the shipping costs like?

Never mind it looks like 3-4 quid only.
They even sell pyritonol, but their citicholine which i believe is CDP looks expensive. I'm gonna give it a go as i lack motivation and energy.

So it seem sits safe to order it ven though it's prescription only. I always thought that would be a problem.

Edited by nito, 07 March 2010 - 12:32 AM.


#5 Perfectionist

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Posted 07 March 2010 - 05:08 AM

I'm uk based too. What the shipping costs like?

Never mind it looks like 3-4 quid only.
They even sell pyritonol, but their citicholine which i believe is CDP looks expensive. I'm gonna give it a go as i lack motivation and energy.

So it seem sits safe to order it ven though it's prescription only. I always thought that would be a problem.


That's weird because today I took 600 mg - no effects.

Later on, I added about another 300mg - nothing notable.

Then again, my tolerance to energy stimulants is out of this world. I can take 600mg of caffeine and still be out of it.

#6 nito

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Posted 07 March 2010 - 08:26 AM

looks like smartpowders sell this stuff too. Seems to be cheaper too. A gram would cost you roughly £1.53 from smartpowders compared to your source which is at £2 at a gram, unless i did my maths wrong.

Edited by nito, 07 March 2010 - 08:41 AM.


#7 mxr808

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Posted 07 March 2010 - 11:58 AM

looks like smartpowders sell this stuff too. Seems to be cheaper too. A gram would cost you roughly £1.53 from smartpowders compared to your source which is at £2 at a gram, unless i did my maths wrong.


Yeah the reason I ordered it from there was because it's already capped and is the Arcalion brand so I can be 100% it's pharmaceutical grade.


As for feeling no effects, I have read quite a few threads on the stuff and it definitely seems variable. People seem to either not react at ALL or feel instant noticeable effects of energy, motivation and alertness. It's fat soluble and requires choline so keep that in mind. I take mine with olive oil and 750 mg choline bitartrate.

#8 Animal

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Posted 07 March 2010 - 08:35 PM

Today my order of Sulbutiamine (Arcalion) arrived and after having taken 400mg and a further top up of 200mg I must say I'm quite impressed with the effects. The wakefulness and mental alertness is amazing and instantly noticeable so I'm really hoping I can use this nootropic in my times of need.

I just wanted to ask a few questions for people who have experience with this.

Do you respond to it?

At what dosage do you respond enough so there is a pronounced effect?

Do you take a choline source with it?

What effects do you experience?

How long does it take for your tolerance to build up?

Thanks.


Tolerance builds pretty rapidly, but it takes 2-3 weeks of daily dosing to lose the effects entirely. I would recommend no more then 3 days a week of up to 800mgs to almost completely avoid tolerance. Personally I don't like it, I find the effects inconsistent and there are far better occasional stimulants with more focused effects, modafinil for one.

#9 mxr808

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Posted 07 March 2010 - 10:05 PM

Today my order of Sulbutiamine (Arcalion) arrived and after having taken 400mg and a further top up of 200mg I must say I'm quite impressed with the effects. The wakefulness and mental alertness is amazing and instantly noticeable so I'm really hoping I can use this nootropic in my times of need.

I just wanted to ask a few questions for people who have experience with this.

Do you respond to it?

At what dosage do you respond enough so there is a pronounced effect?

Do you take a choline source with it?

What effects do you experience?

How long does it take for your tolerance to build up?

Thanks.


Tolerance builds pretty rapidly, but it takes 2-3 weeks of daily dosing to lose the effects entirely. I would recommend no more then 3 days a week of up to 800mgs to almost completely avoid tolerance. Personally I don't like it, I find the effects inconsistent and there are far better occasional stimulants with more focused effects, modafinil for one.


Is modafinil not more at risk of side effects if used regularly though? And is it not also more expensive?

#10 tunt01

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Posted 07 March 2010 - 10:08 PM

anyone have good toxicity/cancer risk data on sulbutiamine? i kind of wonder, given what happened w/ benfotiamine.

#11 nito

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Posted 07 March 2010 - 10:30 PM

Today my order of Sulbutiamine (Arcalion) arrived and after having taken 400mg and a further top up of 200mg I must say I'm quite impressed with the effects. The wakefulness and mental alertness is amazing and instantly noticeable so I'm really hoping I can use this nootropic in my times of need.

I just wanted to ask a few questions for people who have experience with this.

Do you respond to it?

At what dosage do you respond enough so there is a pronounced effect?

Do you take a choline source with it?

What effects do you experience?

How long does it take for your tolerance to build up?

Thanks.


Tolerance builds pretty rapidly, but it takes 2-3 weeks of daily dosing to lose the effects entirely. I would recommend no more then 3 days a week of up to 800mgs to almost completely avoid tolerance. Personally I don't like it, I find the effects inconsistent and there are far better occasional stimulants with more focused effects, modafinil for one.


My friend went to this private surgeon and asked about modafinil, but he wud not prescibe it cus it has way too many side effects. Adding ot that it's pretty expensive, so hard to consider modafinil!

#12 stablemind

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Posted 07 March 2010 - 10:58 PM

Today my order of Sulbutiamine (Arcalion) arrived and after having taken 400mg and a further top up of 200mg I must say I'm quite impressed with the effects. The wakefulness and mental alertness is amazing and instantly noticeable so I'm really hoping I can use this nootropic in my times of need.

I just wanted to ask a few questions for people who have experience with this.

Do you respond to it?

At what dosage do you respond enough so there is a pronounced effect?

Do you take a choline source with it?

What effects do you experience?

How long does it take for your tolerance to build up?

Thanks.


Tolerance builds pretty rapidly, but it takes 2-3 weeks of daily dosing to lose the effects entirely. I would recommend no more then 3 days a week of up to 800mgs to almost completely avoid tolerance. Personally I don't like it, I find the effects inconsistent and there are far better occasional stimulants with more focused effects, modafinil for one.


My friend went to this private surgeon and asked about modafinil, but he wud not prescibe it cus it has way too many side effects. Adding ot that it's pretty expensive, so hard to consider modafinil!



side effects like what?

#13 mxr808

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Posted 07 March 2010 - 11:21 PM

anyone have good toxicity/cancer risk data on sulbutiamine? i kind of wonder, given what happened w/ benfotiamine.

Used search function and had a read. It didn't look very conclusive at all.

Edited by mxr808, 07 March 2010 - 11:33 PM.


#14 medievil

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Posted 07 March 2010 - 11:27 PM

Today my order of Sulbutiamine (Arcalion) arrived and after having taken 400mg and a further top up of 200mg I must say I'm quite impressed with the effects. The wakefulness and mental alertness is amazing and instantly noticeable so I'm really hoping I can use this nootropic in my times of need.

I just wanted to ask a few questions for people who have experience with this.

Do you respond to it?

At what dosage do you respond enough so there is a pronounced effect?

Do you take a choline source with it?

What effects do you experience?

How long does it take for your tolerance to build up?

Thanks.


Tolerance builds pretty rapidly, but it takes 2-3 weeks of daily dosing to lose the effects entirely. I would recommend no more then 3 days a week of up to 800mgs to almost completely avoid tolerance. Personally I don't like it, I find the effects inconsistent and there are far better occasional stimulants with more focused effects, modafinil for one.


My friend went to this private surgeon and asked about modafinil, but he wud not prescibe it cus it has way too many side effects. Adding ot that it's pretty expensive, so hard to consider modafinil!

Nonsense, modafinil hasnt much side effects.
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#15 tunt01

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Posted 07 March 2010 - 11:33 PM

anyone have good toxicity/cancer risk data on sulbutiamine? i kind of wonder, given what happened w/ benfotiamine.

What happened?


befotiamine has been shown to promote tumor growth. and sulbutiamine seems somewhat similar, but i can't say with certainty. i just wonder w/ people taking this kind of stuff, and i can't find any good toxicity studies on pubmed.com.

#16 mxr808

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Posted 07 March 2010 - 11:36 PM

Today my order of Sulbutiamine (Arcalion) arrived and after having taken 400mg and a further top up of 200mg I must say I'm quite impressed with the effects. The wakefulness and mental alertness is amazing and instantly noticeable so I'm really hoping I can use this nootropic in my times of need.

I just wanted to ask a few questions for people who have experience with this.

Do you respond to it?

At what dosage do you respond enough so there is a pronounced effect?

Do you take a choline source with it?

What effects do you experience?

How long does it take for your tolerance to build up?

Thanks.


Tolerance builds pretty rapidly, but it takes 2-3 weeks of daily dosing to lose the effects entirely. I would recommend no more then 3 days a week of up to 800mgs to almost completely avoid tolerance. Personally I don't like it, I find the effects inconsistent and there are far better occasional stimulants with more focused effects, modafinil for one.


My friend went to this private surgeon and asked about modafinil, but he wud not prescibe it cus it has way too many side effects. Adding ot that it's pretty expensive, so hard to consider modafinil!

Nonsense, modafinil hasnt much side effects.


"Side-effects may include Headache, dry mouth, nausea, diarrhoea, constipation, dizziness, blurred vision, stomach pain, tiredness, chest pain, fast heartbeat, flushing, decreased appetite, indigestion, irritability, nervousness, difficulty sleeping, anxiety, depression, abnormal thinking, confusion, numbness or tingling, back pain, neck pain, increased or decreased blood pressure, slow heart beat, excess wind, reflux, vomiting, increased appetite, thirst, difficulty swallowing, altered taste, sore tongue or throat, mouth ulcers, increased cholesterol or blood sugar, sugar diabetes, weight gain or loss, swelling of the arms and legs, muscle pain or weakness, leg cramps, difficulty moving, twitching, sleep disturbance, abnormal dreams, forgetfulness, tremor, migraine, vertigo, speech problems, excessive sweating, acne, minor allergic reaction (such as hayfever), shortness of breath, itchy or runny nose, cough, asthma, nose bleeds, sinusitis, abnormal vision, dry eyes, frequent urination, decreased sex drive and menstrual disorders."

Is too many for me to risk. Already have heart problems.

#17 mxr808

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Posted 07 March 2010 - 11:38 PM

anyone have good toxicity/cancer risk data on sulbutiamine? i kind of wonder, given what happened w/ benfotiamine.

What happened?


befotiamine has been shown to promote tumor growth. and sulbutiamine seems somewhat similar, but i can't say with certainty. i just wonder w/ people taking this kind of stuff, and i can't find any good toxicity studies on pubmed.com.


Wasn't the study only showing that thiamine boosted tumor growth in rats who were basically thiamine deficient?

Wasn't the opposite effect also studied where it inhibited growth?

#18 nito

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Posted 07 March 2010 - 11:40 PM

Today my order of Sulbutiamine (Arcalion) arrived and after having taken 400mg and a further top up of 200mg I must say I'm quite impressed with the effects. The wakefulness and mental alertness is amazing and instantly noticeable so I'm really hoping I can use this nootropic in my times of need.

I just wanted to ask a few questions for people who have experience with this.

Do you respond to it?

At what dosage do you respond enough so there is a pronounced effect?

Do you take a choline source with it?

What effects do you experience?

How long does it take for your tolerance to build up?

Thanks.


Tolerance builds pretty rapidly, but it takes 2-3 weeks of daily dosing to lose the effects entirely. I would recommend no more then 3 days a week of up to 800mgs to almost completely avoid tolerance. Personally I don't like it, I find the effects inconsistent and there are far better occasional stimulants with more focused effects, modafinil for one.


My friend went to this private surgeon and asked about modafinil, but he wud not prescibe it cus it has way too many side effects. Adding ot that it's pretty expensive, so hard to consider modafinil!

Nonsense, modafinil hasnt much side effects.



dress syndrome according to wiki.

#19 mxr808

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Posted 07 March 2010 - 11:42 PM

dress syndrome according to wiki.


Just read the wiki, also Steven-Johnsons Syndrome which can be life threatening.

Edited by chrono, 10 September 2010 - 09:24 PM.


#20 Jurence

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Posted 08 March 2010 - 01:13 AM

Modafinil is dangerous. Use sparingly and with caution.

And from what I have read, it seems sulbutiamine is fine as long as you have a good choline source (raw eggs).

#21 nito

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Posted 08 March 2010 - 01:19 AM

Modafinil is dangerous. Use sparingly and with caution.

And from what I have read, it seems sulbutiamine is fine as long as you have a good choline source (raw eggs).


Is ritalin safer? When you say raw eggs, can't you just take choline bitrate or somthing instead as raw eggs are a bit hard to swallow and stomach?

#22 mxr808

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Posted 08 March 2010 - 01:39 AM

Modafinil is dangerous. Use sparingly and with caution.

And from what I have read, it seems sulbutiamine is fine as long as you have a good choline source (raw eggs).


Is ritalin safer? When you say raw eggs, can't you just take choline bitrate or somthing instead as raw eggs are a bit hard to swallow and stomach?


I'm fairly sure people generally advise using any of what I consider "The Big 3" (modifinil, ritalin, adderall) as a long term supplement. From what I read on ritalin itself I remember reading long term use can induce psychosis within people and also have severe withdrawal symptoms. My research is limited to google, however.

#23 stablemind

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Posted 08 March 2010 - 06:27 AM

Modafinil is dangerous. Use sparingly and with caution.

And from what I have read, it seems sulbutiamine is fine as long as you have a good choline source (raw eggs).


Is ritalin safer? When you say raw eggs, can't you just take choline bitrate or somthing instead as raw eggs are a bit hard to swallow and stomach?


I'm fairly sure people generally advise using any of what I consider "The Big 3" (modifinil, ritalin, adderall) as a long term supplement. From what I read on ritalin itself I remember reading long term use can induce psychosis within people and also have severe withdrawal symptoms. My research is limited to google, however.


I haven't read any long term issues with taking modifinil... people say you can't compare it to adderall or ritalin

#24 Logan

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Posted 09 March 2010 - 02:27 AM

anyone have good toxicity/cancer risk data on sulbutiamine? i kind of wonder, given what happened w/ benfotiamine.


What happened with benfotiamine? I had a bottle left over so I've been taking it every other day or so until the bottles out and was not sure if I was going to continue to take it after. I guess I might as well dump it now if I'm not going to take it anymore when I run out.

#25 Logan

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Posted 09 March 2010 - 02:29 AM

anyone have good toxicity/cancer risk data on sulbutiamine? i kind of wonder, given what happened w/ benfotiamine.


What happened with benfotiamine? I had a bottle left over so I've been taking it every other day or so until the bottles out and was not sure if I was going to continue to take it after. I guess I might as well dump it now if I'm not going to take it anymore when I run out.


OOps, just read through the rest of the thread and realized my question was already answered.

#26 nito

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Posted 11 March 2010 - 04:38 AM

Would customs not take this supplement if i ordered it to the uk since its prescription based?

#27 Stan100

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Posted 11 March 2010 - 11:19 PM

Got some sulbutiamine, and first day was great. I (perhaps stupidly) eyeballed what looked to be about 500mg. Great effects, I knocked out a project, studied for a test, blew through some old magazines and finished the test first. Took some more today and only felt "okay". I'm definitely holding onto it for the rainier days.

#28 ian1983

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Posted 12 March 2010 - 12:05 PM

Would customs not take this supplement if i ordered it to the uk since its prescription based?


I ordered some through smart powders and had no problems getting it through

#29 Thorsten3

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Posted 12 March 2010 - 11:33 PM

As long as it's not a controlled drug it's usually fine

anyone have good toxicity/cancer risk data on sulbutiamine? i kind of wonder, given what happened w/ benfotiamine.


What happened with benfotiamine? I had a bottle left over so I've been taking it every other day or so until the bottles out and was not sure if I was going to continue to take it after. I guess I might as well dump it now if I'm not going to take it anymore when I run out.


OOps, just read through the rest of the thread and realized my question was already answered.



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#30 mxr808

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Posted 02 April 2010 - 03:29 AM

I know I'm kind of doing a shameless bump but I'd just like to inform people that I'm still taking Sulbutiamine and I'd advise anyone who hasn't yet to give it a shot. One of the best things I've ever done. Rolling around to exams now and I'm whacking out revision like I never thought I could. This substance has had such a positive effect. Haven't had any loss of effect yet but have cycled it a bit.




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