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Ridiculously large piracetam doses


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#91 Major Legend

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Posted 12 June 2011 - 05:41 AM

am I the only one who feels piracetam doesn't really enhance any cognitive abilities, but just makes your personality more flat, focused and wired with visual clarity? Its not hard to see how this can be mistaken as a cognitive enhancer, especially at higher dosages.

For the record I don't feel anyone claiming the magical effects of racetam, write beautifully as they seem to believe. It just seems they believe they are enhanced by that wired feeling so they are writing longer posts, and confidently using the full breadth of their vocabulary. Though the content being delivered isn't actually much more intelligent or witty than normal.

I would even go further to suggest that Piracetam may impair wit and humour to some extent. I'm on piracetam at the moment, and I definitely don't feel that fun vibe anymore, rather I just feel very flat and focused. Its not fun :(

edit: in fact I can even attribute the visual clarity to a reduction in being stimulated by my environment.

Edited by Major Legend, 12 June 2011 - 05:47 AM.

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#92 kache

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Posted 14 June 2011 - 12:01 AM

am I the only one who feels piracetam doesn't really enhance any cognitive abilities, but just makes your personality more flat, focused and wired with visual clarity? Its not hard to see how this can be mistaken as a cognitive enhancer, especially at higher dosages.

For the record I don't feel anyone claiming the magical effects of racetam, write beautifully as they seem to believe. It just seems they believe they are enhanced by that wired feeling so they are writing longer posts, and confidently using the full breadth of their vocabulary. Though the content being delivered isn't actually much more intelligent or witty than normal.

I would even go further to suggest that Piracetam may impair wit and humour to some extent. I'm on piracetam at the moment, and I definitely don't feel that fun vibe anymore, rather I just feel very flat and focused. Its not fun :(

edit: in fact I can even attribute the visual clarity to a reduction in being stimulated by my environment.

In my case it's exactly the opposite, sadly. My personality becomes more pronounced and lively when I'm on piracetam, while when I'm off it's very flat and similar to the personality of a depressed person.

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#93 tigermountain

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Posted 15 June 2011 - 02:49 PM

am I the only one who feels piracetam doesn't really enhance any cognitive abilities, but just makes your personality more flat, focused and wired with visual clarity? Its not hard to see how this can be mistaken as a cognitive enhancer, especially at higher dosages.

For the record I don't feel anyone claiming the magical effects of racetam, write beautifully as they seem to believe. It just seems they believe they are enhanced by that wired feeling so they are writing longer posts, and confidently using the full breadth of their vocabulary. Though the content being delivered isn't actually much more intelligent or witty than normal.

I would even go further to suggest that Piracetam may impair wit and humour to some extent. I'm on piracetam at the moment, and I definitely don't feel that fun vibe anymore, rather I just feel very flat and focused. Its not fun :(

edit: in fact I can even attribute the visual clarity to a reduction in being stimulated by my environment.



I am on the fence about piracetam. I've tried it at high-ish doses (7g) and lower doses 800mg... I do find that it enhances the senses somewhat - like you said, I am more stimulated or sensitive to my environment. My body feels more sensitive, too... like an awareness of breathing and heart beats, which I find distracting and makes it feel a bit druggy...

I usually feel awesome when I first take it.. slightly euphoric, great for working out (I can work out for longer without getting bored!). Then, I am more bleh and sleepy and by the end of the day (even if I take a bit more), I feel a bit irritable, don't feel like talking..

One particularly good thing that I noticed is that I am able to articulate fleeting thoughts, the ones that normally are too vague or complex to express... I'm able to 'capture' them.. make them real. However, my writing is quite sloppy when on higher doses. Also, I speak reeeaaalllllyy slloooooowww... my boyfriend has noticed this and it drives him mad because it takes me so long to answer a simple question. Even on low doses. But I am very precise and um.. interesting.. in the things I say. I don't think the brain works faster on piracetam, but there seems to be more interconnectedness between your thoughts.

#94 Lost Soul

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Posted 15 June 2011 - 03:53 PM

i'm wondering what constitutes actual hypomania. i would get into episodes where i was quick witted, and articulate as hell. this was always synchronized with extreme psycho motor agitation.restlessness. my appreciation for music would go up ten fold, social anxiety, gone. i felt like my mind was sped up immensely. i could take on anyone. i think i had some slight paranoia, but i might've always been like that. this effect was never consistent and was usually mastered by playing around with the doses. the thing is i'm usually the complete opposite of all this, so it's just a mindfuck for me how i can change so much through this one supplement

#95 ultranaut

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Posted 16 June 2011 - 04:39 AM

I've been trying to find a sustainable method of inducing hypomania. It's difficult because the map becomes harder to read the further into the territory you go. Or alternately: subjectivity distorts self-experimentation and so the best I can attain is a meta-subjectivity that isn't as objective as it seems. Thus far semi-regular piracetam + d-amp has been working fairly well (I think). There's way too many factors to account for everything, but the broad direction has been positive. I teeter on the brink of hypomania most of the time, sometimes I cross over for a few hours or a few days. Occasionally things tip the other way. I am generally productive and happy (I think!).

#96 genseb7

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Posted 13 November 2011 - 02:40 PM

I've been trying to find a sustainable method of inducing hypomania. It's difficult because the map becomes harder to read the further into the territory you go. Or alternately: subjectivity distorts self-experimentation and so the best I can attain is a meta-subjectivity that isn't as objective as it seems. Thus far semi-regular piracetam + d-amp has been working fairly well (I think). There's way too many factors to account for everything, but the broad direction has been positive. I teeter on the brink of hypomania most of the time, sometimes I cross over for a few hours or a few days. Occasionally things tip the other way. I am generally productive and happy (I think!).



Me too! I'm so much more productive. I've never been full blown manic but honestly it sounds interesting. d-amp is dextroampheatime, yes? if so I agree. I've also been drinking lots of green tea(I find the adderall will make me get sick and feel like shit if I take it for too long on end. I found out (accidentaly) occasional use of psychedelics can really pull you back into hypomania when you feel like your slipping into depression. Also constantly working on my self talk has done a lot more for me then self talk gets credit for, probably since self talk isn't as sexy as amphetamines.

Anything new on the hypomania?

#97 sam7777

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Posted 13 November 2011 - 08:18 PM

Read my post about the fish pills and neuroendocrinological disorders. Hypomania is phenominally complex.

Basic chemistry, nothing is free. When trying to think of how to turn the brain on full speed, you need to focus on how to turn the body on full speed. Makes me think of this show I watched about how the first time a guy tried meth he set the school record for the long distance shot put. Not saying that meth is not lethal and addictive, just pointing out the neuroendocrinological aspect.

I have lately been thinking of a trifecta approach of combining cortisol limiting compounds and diet and exercise, with strong 5ht2a agonists- psychadelicas, and powerful anti-oxidants.

With these states, the underlying risk of excitotoxicity is a nasty reality, and the fact that most people on this board probably have mineral imbalances and endocrine disorders further complicates the mess.

I read something about how 5-ht2a receptor agonization leads to increased oxytocin and oxycotin expressing factors as well as increased CRF and ACTH.

Oxytocin and low dose mu and delta opioid receptor agonists are fantastic for learning in hypomania in my opinion. Frankly, so is cortisol. Cortisol is a double edged sword though, and this is probably the ultimate limiting factor.

I find myself always asking the same ruminating question: I want to be in a massive cortisol state, but I know my body cannot handle it.

Pain, discomfort, nausea, headache, dizziness- these are signs of inflammation and oxidation. Any nootropic combo that can produce some significant pain reduction and anti-oxidant capacity sounds promising for that reason. This could keep dynorphin in check, and keep dopamine levels up.

This makes me remember how I read about certain breeds and strains of cannabis being highly stimulating and pain relieving at the same time. I still kid myself with the hope that I can find a strain of cannabis that makes me want to do calculus.

#98 1thoughtMaze1

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Posted 22 November 2011 - 04:01 AM

I thought this thread was about high doses of piracetam... Too many people talk sh*t about unrelated stuff mann

#99 medievil

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Posted 22 November 2011 - 06:12 PM

rwong rhead

Edited by medievil, 22 November 2011 - 06:12 PM.


#100 medievil

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Posted 22 November 2011 - 06:14 PM

I've been trying to find a sustainable method of inducing hypomania. It's difficult because the map becomes harder to read the further into the territory you go. Or alternately: subjectivity distorts self-experimentation and so the best I can attain is a meta-subjectivity that isn't as objective as it seems. Thus far semi-regular piracetam + d-amp has been working fairly well (I think). There's way too many factors to account for everything, but the broad direction has been positive. I teeter on the brink of hypomania most of the time, sometimes I cross over for a few hours or a few days. Occasionally things tip the other way. I am generally productive and happy (I think!).



Well amt is your best bet, pretty much the holy grail for a log of things, cant use it muself anymore tough as i screwed myself up with amp.

end discussion here and come to my thread if you want to know more, its in the regime section.

I apologize for hijacking your place again.

#101 sambocyn

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Posted 23 November 2011 - 05:36 AM

Thanks for the Reishi recommendation. I've never heard of it. Based on your description it sounds interesting to me although Animal's POV contradicts it's mood elevating ability. Guess I'll have to try it and find out.



You should try it at least 2 weeks. It builds up slowly and one day you say, hey I can do more.

The problem I see with piracetam mega dose (beside becoming god and maybe your brain ?) is the extra toll on your kidneys. There is a thread about this.


I'm young and invincible, don't worry.

Day 3 of 40-80g/day. Everything is smooth sailing thus far. No telekinetic or deistic powers yet, unfortunately. It really is important to point out that my rhetoric and diction in both spoken and typed language is in every way superior to that before I was on mega-dosing Piracetam. Moreso than when I was doing 2/g a day.

I have enjoyed laying in my hammock and studying much more over these last few days. The fractal essence of trees, clouds and nature are very sweet to the senses.


oh look, its isochroma jr


lol

#102 sambocyn

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Posted 23 November 2011 - 05:48 AM

Today it makes me very sleepy.

I may go to 20 gram of piracetam a day to see what it does, i expect it to make me sleepy for a few days untill the benefits kick in.

Did you notice sleepyness ark? And how long did it take to go away.

NMDA antagonism should have a mood stabilising effect so i'm expecting that 60mg of memantine will keep me from going manic.

I'm also on galantamine and alcar.


(hey, i know this is a year ago, i just joined, but in case it's still relevant...)

hmm, speaking personally and from anecdote (as we all are), 10-20g, will NOT induce hypomania. perhaps hyperthymia, which isn't bad. and it would take maybe hyper-isochroma masses of piracetam to induce actual DSM-mania in someone without any history of mood disorder. having said that, i wouldn't (just yet) stack with this memantine stuff. it is not necessary to prevent hypomania. even if safe, it would distort (possibly harm) your piracetam experience.

if you are really concerned about your mood, slowly increase your dosage over the course of weeks. or try aniracetam, which is anxiolytic.

as for sleepiness, try 600mg choline (as in, pure choline; e.g. i have 650mg choline bitartate capsules which contain 293mg actual choline). though i've been doing piracetam on and off for almost a year now, and that's what i'd do, but ymmv.

Edited by sambocyn, 23 November 2011 - 05:56 AM.


#103 outsider

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Posted 23 November 2011 - 11:12 AM

Today it makes me very sleepy.

I may go to 20 gram of piracetam a day to see what it does, i expect it to make me sleepy for a few days untill the benefits kick in.

Did you notice sleepyness ark? And how long did it take to go away.

NMDA antagonism should have a mood stabilising effect so i'm expecting that 60mg of memantine will keep me from going manic.

I'm also on galantamine and alcar.


(hey, i know this is a year ago, i just joined, but in case it's still relevant...)

hmm, speaking personally and from anecdote (as we all are), 10-20g, will NOT induce hypomania. perhaps hyperthymia, which isn't bad. and it would take maybe hyper-isochroma masses of piracetam to induce actual DSM-mania in someone without any history of mood disorder. having said that, i wouldn't (just yet) stack with this memantine stuff. it is not necessary to prevent hypomania. even if safe, it would distort (possibly harm) your piracetam experience.

if you are really concerned about your mood, slowly increase your dosage over the course of weeks. or try aniracetam, which is anxiolytic.

as for sleepiness, try 600mg choline (as in, pure choline; e.g. i have 650mg choline bitartate capsules which contain 293mg actual choline). though i've been doing piracetam on and off for almost a year now, and that's what i'd do, but ymmv.



Exactly (about nmda and memantine) I would recommand instead, working with the original melecules (the ones that were used to create you in the manufacturing plant ;) like magnesium. It was made to plug in the nmda and stop it from over working.. cost ? Virtually nothing if you buy Epsum salt. And instead of working with nefiracetam you could take some more glycine and D-serine which work allosterically a bit like nefiracetam to modulate the glutamate effect on the nmda receptor, increasing the effect, magnesium and Zinc prevent over working while adding extra, direct, cognitive benefits. And the side benefits are these molecules/atoms are made to synergise throughout the rest of your body.

There seems to be 2 allosteric site binding agonists possibility for the nmda receptor, Glycine and d-serine are the ligans.

For glycine:
http://www.jneurosci...3/1088.full.pdf

Glycine and d-serine:
http://www.ncbi.nlm....pubmed/18805436

And don't forget that the racetam family of drugs are developed from the tweaking of the pyroglutamamic acid (amino acid, also known as pyroglutamate) from the start in the laboratories.

#104 Isochroma

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Posted 10 April 2013 - 03:08 AM

Thank you Wurzel Bagman!

Your report is a crystal distallation of my own experiences using high-dose Piracetam.

There is nothing like the superb clarity, energy, visuals and becoming God - it's call the God Molecule or God Particle for that reason.

If you find that even the optimal 30g/day isn't working like it used to, do realize that even while Piracetam is truly the most powerful neural accelerator, it is also the weakest racetam to restore actual energy generation.

So Piracetam barely 'pays' for all the brain speedup and depthup it causes.

As you age the energy equation tilts and eventually you may run into fatigue.

In that case you can add Oxiracetam (about 1g OXI / 4g PIR). Oxiracetam has a higher quantum level than Piracetam and boosts mitochondrial energy conversation capability higher than any dose of Piracetam can. I call it PerOxiClear - the best possible mix of PIR/OXI and overall the best stack I have ever made.

However, none of the other racetams have PIR's accelerant feature - they are quiet in nature but provide other benefits.

I am still taking 5g x 6 per day Piracetam but I always stack on top of it a truly powerful mitochondrial energy restorer. For only the purpose of enhancing mitochondrial output (anti-brain-fatigue) and according to my tests the racetams listed in order of decreasing power are:

1. Pramiracetam
2. Oxiracetam
3. Aniracetam
4. Piracetam

Sunifiram is not a racetam but it's more powerful than those listed above for energy restoration.
I have tested Coluracetam but stacked with Piracetam and Pramiracetam due to circumstances so I cannot tell its effect alone.

#105 Isochroma

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Posted 10 April 2013 - 03:50 AM

As for saturation dosing, a recent study found 4.8g to be optimal so I dose at even five grams.

And for 'useful life' which means how long it lasts before any detectable signs of dropoff - three hours for all racetams except Aniracetam: two hours for that one.

Thus we now have the success-without-excessive-wallet-drainage formula for Piracetam: 5g once each 3 hours all day long.

For me that means six doses per day totalling 30g Piracetam which is my current regimen.

I buy 2kg Piracetam every other month.

And for the alternate months I buy Piracetam's double: the higher-energy racetam which will provide for Piracetam's mitochondrial gap and also as secondary benefits their improved visual/procognitive effects.

For the last six months Piracetam's dancing partner has been Oxiracetam and lately, Pramiracetam.

Finally I have moved up yet again: 15mg doses of Sunifiram complement the Piracetam thus preventing eventual fatigue.

I also notice that stacking Piracetam with any other racetam prevents the angry bitchiness that randomly occurs with Piracetam alone after sufficient months of use.

Edited by Isochroma-Reborn, 10 April 2013 - 03:50 AM.


#106 Mr. Pink

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Posted 10 April 2013 - 04:38 AM

As for saturation dosing, a recent study found 4.8g to be optimal so I dose at even five grams.

can i have a citation please. very curious about the variables they studied

#107 Balfi

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Posted 26 June 2014 - 08:10 PM

Since this is my first post (but long time reader) I am not able to post links.

But to read about the 4.8g studies with Piracetam, please google this:
 

PIRACETAM DOSAGE - Why you should be taking 4.8 grams / dose

Written by ScienceGuy



#108 Introspecta

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Posted 26 June 2014 - 10:18 PM

You bumped a year old thread to say this? I don't get it. Terrible first post. hahahhaha. jk. If your going to bump old threads you might want to have something a little more useful to say. Just a suggestion.



#109 Balfi

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Posted 27 June 2014 - 04:27 AM

You bumped a year old thread to say this? I don't get it. Terrible first post. hahahhaha. jk. If your going to bump old threads you might want to have something a little more useful to say. Just a suggestion.

 

Hopefully someone finds it helpful in the future, or perhaps in 500 years from now after they crawl out of their cryo tube.

Isn't the date sort of irrelevant? This is LongeCity after all. Just a comment.



#110 Introspecta

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Posted 27 June 2014 - 09:27 AM

Yeah it is and it isn't. Its just that all of this was discussed extensively around that time so now that you bumped it unless something new was added it will most likely not get any more comments.



#111 Balfi

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Posted 27 June 2014 - 02:08 PM

At least now it is a succinct flow of information since someone asked a question and it was answered. It's like a classroom - sometimes someone asks a question that other people want to hear, or are interested in hearing the answer to once it is asked. I'm not really concerned with the priority of "letting it die" or not "bumping it". Why should we let it die anyways? I do advocate unlimited lifespans!

ScienceGuy's remarks on dosing 4.8g of Piracetam per dose are very well documented and are a result of many different cited studies. It seems worthwhile to relay that information, especially in this forum about mega dosing Piracetam (and I did not see it mentioned in the other pages).

Forums themselves are like cryotubes; one can by bring that discussion to life with a simple Google search and stretch of the eyes.

I intend no further comments justifying my post on this matter! If you wish to give me any remarks about forum etiquette  - PM me. I won't include anymore on the matter here!

To whoever reads this in 2050: bump it!



#112 maik2013

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Posted 27 April 2016 - 10:18 AM

There was this other guy, who started megadosing Piracetam, i can't find it now. He became supersmart and successful. He also became super social and he also had one night stands for the first time in his life. He was verbally so fluent that he could guess what people would say and think, well, until it stopped working. He didn't do any crazy mania stuff that ruined his life, it just stopped working and he became the normal bloke again he was before. It was very depressing for him. 


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#113 maik2013

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Posted 01 May 2016 - 08:13 AM

I tested Pira Mega (Geratam) last week again and it worked great. Mega for me is 12g twice a day dissolved in water. Even 5g is totally different than 12g for me. 12g has stimulant properties for me, i was listening to loud techno music and still work on the most complicated task(normally impossible for me), while generally not being in the best mood( low base state) at the moment. So i ENJOYED myself while being very productive. Great experience. It's consistent with my experiences last summer. I decided to do this stack only  twice per week, because i really want it to last this time. Two other days a week i take Phenotropil and for the other three days i take Aniracetam the night before. Ani makes me tired, but the nootropic effects linger on the next day. Isochroma does this too. But i found out independently from him. If this stack gets my productivity index up for more than three months i'll report back.

 

P.S. You can find Isochroma on Reddit. https://www.reddit.c...sochroma-Reborn

His current regimen is: 

Noopept: 50mg x 5 / Day = 250mg / Day Total

Aniracetam: 1.2g x 5 / Day = 6g / Day Total
Piracetam: 6.5g x 5 / Day = 32.5g / Day Total

 

+ 45mg DXM and 21 mg Melatonin at night.  :laugh: 

 

But i still find valuable information in his posts, but apparently he often writes if i had more money i would take xy doses, so i consider his plan a fail. What's the point of taking so much if it doesn't pay off, but a fun way to live. He should get a career as a racetam expert going.


Edited by maik2013, 01 May 2016 - 08:53 AM.





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