492 replies to this topic

[Stephen Bajon]

Best to use 100mg of P 5 P along with 200mg of Phenylalanine along with your 5 mg of Eldyprl as it makes it work like a charm. No one that takes it is ever depressed that I have seen. Need Rx from M D for it though.

[Twindaddy37]

I agree with a poster talking about people making all kinds of claims about 60mcg or 200mcg doses, and getting headaches and this and that- likely placebo. I find that at several milligrams it has somewhat of an effect, like perhaps 2mgs and up, a slight uptick in mood with increased color saturation. That is about all i have noticed with MB. I use it as a pick me up a few days a week. I have tried it at very low doses with no noticeable effect, but perhaps it does have an effect i am unaware of. 

[capob]

My experience, after about 3 years: 

 

- 3mg-10mg on tongue (back top of tongue) improves workout performance by decreasing perceived physical effort.  Also, slight motivator.

- 10mg in cup of water does nothing

- 1mg intranasal via neti pot does nothing (except burn)

 

 

[blacksalt]

Rather than post in a dead thread [ http://www.longecity...mao-inhibition/ ] I did want to post about a case of suspected serotonin toxicity I likely experienced as a result of dosing MB while taking my regular dose of ADHD medication [ extended release methylphenidate aka Concerta ]

 

I recently took a drop or two of MB as a nootropic but forgot it's a Monoamine oxidase inhibitor (MAOI)...

 

And, with the Concerta [ extended release methylphenidate] I'm taking ... not a good combination.  

 

Serotonin toxicity can occur quickly [ within a day ] but also fortunately stopped in its tracks quickly if one realizes what is going on...

 

I've had these weird sensations of hollowness in my chest and sometimes extending to my arms. It physically felt like what 'anxiety attacks' were described to me as but I didn't feel anxious - just the physical symptoms. Part of me didn't want to consider the possibility my dose of Concerta was too high but nevertheless I took only half my dose this morning... but while driving, the same uneasy feeling comes up. 

 

Then I start thinking -- what the Hell might it be? I can't be suddenly developing sensitivity ... can I? Then I remember... recently in the past week, I've been dosing a glass of water with one or two drops of Methylene Blue. [ usually I do it only once in a while but somehow I've managed to remember to take it almost each day ... ] And, voila! the very likely cause...

 

Usually I'm pretty open with my prescribing physician but I suspect if I share this incident with her tomorrow during my monthly ADHD prescription re-up appointment, she'll likely take me off the Concerta entirely. Earlier this year, after missing one appointment (and therefore one week of medications), she dropped my dose to 25% for weeks and titrating back up only after 90 days. 

 

 

[boroda]

Started taking 15mg/day a month ago. Feeling good mood boost and tons of energy - but that is not what surprised me a lot because that was expectable. What really surprised me was that it cured seborrheic dermatitis on my face almost instantly (for those who don't know what that is: it's kind of eczema on face, red flaky inflamed itchy skin, incurable decease which I tried to fix last 7 years. And now - after just 5 days on MB - skin on my face became ABSOLUTELY clear. Unbelievable. I tried 1 000 000 things to fix that shit and I was already hopeless and ready to live with it forever. MB is amazing.

[blacksalt]

I know seborrheic dermatitis is a different condition from eczema herpeticum, but my brief search for research indicates that MB has been positively cited in studies involving the latter. ( https://www.ncbi.nlm...v/pubmed/170870 ) 

 

How much MB is "15mg per day" as you indicated? 

 

 

 

 

[boroda]

How much MB is "15mg per day" as you indicated? 

 

1g of MB powder dissolved in 100ml of water.

1.5ml of solute (measured by syringe)  = 15mg of MB

[blacksalt]

Thanks!

[Pizzarulzz]

Can someone tell me how to get this in India , any brand name of anything

[boroda]

Can someone tell me how to get this in India , any brand name of anything

 

I bought 10g bag from local chemicals supplier, I think you can try to ask chemicals suppliers in Delhi. Don't forget to tell them you need at least 99.5% purity.

[mag1]

Anyone know what specific form of methylene blue was used for the human clinical trials for Alzheimer's?

 

The below number CAS numbers are all very similar and are called Methylene Blue, though they are slightly different.

 

 

61-73-4

122965-43-9
152071-32-4
7220-79-3

Edited by mag1, 09 December 2017 - 01:52 AM.

[MKultra]

Today i got my bottle from Mitolab, very excited to try but i guess i need to stop taking St. John's Wort fist, obviously i dont want to get serotonine syndrome.

 

So i take it that its best to place it on the back of the tongue? after how long time do you swallow it? I find it hard to keep anything there for very long due to saliva,  swallowing reflexes etc.

 

[mbdrinker]

Except for the fact that serotinin ads turn you into impotent... I would better suffer than get pleasure from ads