LONGECITY

If there are amny people here, who use some strategy for suppressing some aging change, and other, who do not want to use exactly this strategy, we can make a study for the effect of the strategy.

For example, if many females here use on daily basis anti wrinkles cremes, and if they are willing to do that, we can do the following: Photos of a wrinkle or wrinkles of some part of the face can be photograped - not the whole face ; the photos can be taken even with a gsm camera - and compared after periods of time usage of a creme brand, like creme 1 after one week, after two weeks, after two months. On that way will be understood if the cremes work at all and which brand is the best. People, who have wrinkles and do not want to use cremes, may photograph their wrinkles and the changes of their wrinkles to be compared with the changes of the wrinkles of the people, who have used creme. On this way can be understood if the cremes have an effect over the wrinkles, or not. Since the people, who are using the strategy use it anyway and the people who do not use it - do not use it anyway noone looses nothing. But the result can be of benefit for all participants.

If there are amny people here, who use some strategy for suppressing some aging change, and other, who do not want to use exactly this strategy, we can make a study for the effect of the strategy.

For example, if many females here use on daily basis anti wrinkles cremes, and if they are willing to do that, we can do the following: Photos of a wrinkle or wrinkles of some part of the face can be photograped - not the whole face ; the photos can be taken even with a gsm camera - and compared after periods of time usage of a creme brand, like creme 1 after one week, after two weeks, after two months. On that way will be understood if the cremes work at all and which brand is the best. People, who have wrinkles and do not want to use cremes, may photograph their wrinkles and the changes of their wrinkles to be compared with the changes of the wrinkles of the people, who have used creme. On this way can be understood if the cremes have an effect over the wrinkles, or not. Since the people, who are using the strategy use it anyway and the people who do not use it - do not use it anyway noone looses nothing. But the result can be of benefit for all participants.

What could be done if a member of a wrinkle project is going to experiment with one new ingredient for an anti-wrinkle creme? Perhaps someone could become aware about a plant substance which has been proven good for the skin and mixes it into one of the cremes only to get better wrinkle treatment? So in case it will become a project and the benefit for all participants must be prioritized, we do not want that someone is patenting the new mixture and makes a profit with it without other participants gaining profits too. So the best would be to open up a blog called DID which stands for Durable Idea Discussion. There should be the durability of all sorts of ideas supportive to immortality, like the idea of engineered negligible senescence de Grey and his colleges revealed in "Time to Talk SENS: Critiquing the Immutability of Human Aging" http://www.kronoslab...1/deGreyAD3.pdf 2002, New York Academy of Science.

Everyone who is testing a specific creme or a new mixture should publish something about the ingredients on the above mentioned DID blog. Some details of patent law require expert knowledge I could not learn. Nevertheless, it seems to me that if a blog member is trying to patent a new mixture, other blog participants could probably act against it by telling a patent authority that this would be against the terms and conditions of the project. So I believe important things for the durability of life should be in the public domain.

Perhaps something like DID exists and I have not found it yet, there are two related pages: www.halfbakery.com and www.ideablob.com while the latter site has not opened up when I tried to access it today. So it seems to be gone with bankruptcy as http://amysampleward...ob-says-goodbye has announced it. The blogs on Longecity seem to be much suitable for single individuals and not so much for groups, so someone has to create a new one somewhere. Would that be all right?

I am sorry for the misunderstanding.
I meaned people, who use APPROVED - already patented - cremes
There are many anti wrinkle cremes on the market.
So, if there are enough people, who use different brands, we should be able to verify which is the best brand. Thats all.

So, are there volunteers, who use a preffered creme for wrinkles, and are willing to say the brand, to photograph a wrinkle after week, month and after several months?

Among results from dogpile.com searching for anti-wrinkle test: Consumer Reports Tests Anti-Wrinkle Creams http://pittsburgh.cb...-wrinkle-creams on July 19, 2011, by CBS Pittsburgh. They used an outside lab and a total of 79 people. The report contains recommendations what to do instead of using expensive anti-wrinkle creams, citations: moisturizing your skin day and night... drinking plenty of water...

Shielding with sun lotion and eventually something like http://www.glovesina...-skin-care.html seems to be a good idea too.

I dont know about wrinkle creams, maybe, but other things that come to mind for this sort of thing are things like CR, resveratrol, astralagus and metaformin. If you find some participants then please do direct them to post in this topic. That would help a lot in considering it further.

I dont know about wrinkle creams, maybe, but other things that come to mind for this sort of thing are things like CR, resveratrol, astralagus and metaformin. If you find some participants then please do direct them to post in this topic. That would help a lot in considering it further.

There are many problems with this suggestion:

* No placebo is possible
* No double blind, results interpreted by biased people
* Self selected individuals creates a selection bias
* Control group?
* Very unlikely that you will have enough participants (> 1000)

Even all of the problems, the idea to be tested any of these things is not bad after all.

There still can be done a qualitive research, if the people, who want to participate, be devided in two groups - who use the method (working group) and who do not use it (control group). I don't mind to be in the control group of any of these studies since I do not use neither anti wrinkle cremes, nor CR, nor resveratrol, nor astralgus nor metformin.

I think that a more general approach could drive up thought in this area to potentially inspire a more concerted approach.

How many participants do you think you would need for photographing their wrinkles?

Well, the answer of this question is "as many as possible". However if we manage to collect 100 photographed wrinkles of before and after 1 or 2 months of treatment it will be good enough. There may even not be a 100 people, but lets say to be tested ten "cremes" with ten people each will be fine. Unfortunately, no one so far from the forum has participated.

What about 1 cream to start off with, 3 participants minimum with 2 control group minimum? I know its not as ideal to get fewer but what is the least amount of people that would make it worth it?

This will be fine. What is important to have the photo before, the data about the brand of the creme, how the person uses it, and the photo after 1 or 2 months. If more participants gather after time, the information about their results will be addable to the previous ones, since it is not important the time, that they started, but it is important for how long do they use the creme, the active molecule of the creme, and how do they use it.

i think this is a good initiative, the more things like that we have, the nearer we get to a result. we have to stop thinking about obstacles and start thinking about possible solutions. I'm all for it!

Thank You VioletVol

This will be fine. What is important to have the photo before, the data about the brand of the creme, how the person uses it, and the photo after 1 or 2 months. If more participants gather after time, the information about their results will be addable to the previous ones, since it is not important the time, that they started, but it is important for how long do they use the creme, the active molecule of the creme, and how do they use it.

We are sponsored by Juvess, (see banner at bottom of this topic) and a guy that runs it has been a part of Imminst for a long time. Why dont you find at least 3 participants to use a cream, and 2 controls to just take pictures, and contact Chris a Juvess and see if they would be willing to send free samples to 3 or more people for this experiment. They would get some nice attention for their product through the continuous posts that journal this process. You will have to explain to potential participants what they have to do and then be sure that they will follow the instructions. I think that Violett will be willing to participate as one. Can you search skin care topics in the forum for participants?