68 replies to this topic

[gizmobrain]

Hey OP, where'd you go? Any updates?

Thought I'd check in and let you know where I'm currently at (the short version anyway; I'm on my cellphone).

I ordered some Jarrow sublingual methylcobolamin, and from the very first day, I've noticed a reaction. I feel generally pretty amazing. My normal tiredness and muscle fatigue is gone.

I've noticed a few side effects. After reading information over at http://forums.phoeni...e-Chelation-... both my symptoms and side effects seem to line up.

I think I'm going to walk through their b12/folate deficiency protocol ASAP. Quite possibly my ADHD-PI that my doctor had me all coked up trying to treat may just be a moderate vitamin b deficiency caused by a genetic polymorphism causing me to not make the enzyme that converts folic acid to folate, or cyanocobolamine to its active form.

Seems like an amazing step in the right direction.

[HighOrder]

Devin, any updates on your regimen?

[Magnet]

When I say "stimless" I mean that I am not willing to take typical ADHD stimulant medications. My goal is to fully treat my Adult ADHD (predominantly inattentive) and attain a good working memory. I wish to only dose major supplements 2x/day.

Morning:

• Selegiline (capsule): 5mg
• DL-Phenylalanine (sublingual): 500mg
• Huperzia (1%): 20-30mg (200-300mcg Huperzine A)
• Pinebark Extract (90% OPC's): 100-150mg
• Ashwagandha (1.5%): 470mg
• Gotu Kola (dried, whole): 450mg
• Methylene Blue: 3mg
• Vitamin C: 500mg (to activate MB)
• Magnesium (Oxide): 250mg
• Zinc (Gluconate): 12.5mg
• Fish Oil: 1000mg
• [Protein Breakfast] + Coffee + Black Tea

Mid-Day:

• \DL-Phenylalanine (sublingual): 500mg
• Huperzia (1%): 20-30mg (200-300mcg Huperzine A)
• Pinebark Extract (90% OPC's): 100-150mg
• Fish Oil: 1000mg
• \Somewhere between, I usually have Black Tea. Sometimes coffee, sometimes zinc, sometimes fish oil...

Evening:

• Ashwagandha (1.5%): 470mg
• Zinc (Gluconate): 12.5mg
• [Big Supper]

If I need energy, I'll grab some Green Tea.

Night:

• Gotu Kola (dried, whole): 900mg
• Magnesium (Oxide): 250mg

I get uppity right before lunch, all light headed. After lunch, I crash into a stooper for 3 hours. I come up around 5pm and am alive till 7pm when I crash again. I hate dosing 4x a day. 2x a day is enough. The only switch I'm proposing is moving Ashwagandha + Zinc to Mid-Day. Ashwagandha seems to stabilize me at a little higher mood than normal, which is good.

For those of you who are skeptical about Huperzine A, don't be. Combined with the Selegiline, I finally have self control. My memory is finally good. Not the best, but better than it has ever been. It's not for everyone, but it is for me.

Potential Additions:

• Triple Strength Lecithin: 400mg PS per cap (take 3 at a time, 2x/day)
• Olive Leaf Extract (18% Oleuropins): 500mg (2x/day)
• TMG + NAC: 500mg + 200mg (2x/day)
• Lithium Orotate: 100mg (at night?)
• Jiaogulan (95% Gypenosides): 50mg (2x/day)
• Astragulus Root (12:1) + Chitosan: 1000mg + 500mg (at night)
• Ginkgo (24/6/5 std): 120mg (3x/day)
• Curcumin (95%): 500mg (2x/day)
• Picamilon: 100mg (at night)
• PQQ: 5mg (4 weeks at a time, 1x/day)

Please speak up if you notice any potential synergies or benefits with these suggestions.

I've already asked for the Triple Strength Lecithin for Christmas... I find that one synergizes with Huperzine A more than anything in the world. Lithium is just... well a great nootropic at its nootropic dose. Olive leaf has COMT inhibitors... and I've noticed a lot of positive benefits from extra virgin olive oil, just curious if it is the oleuropin or just the oil giving the effects. TMG + NAC I heard was quite stimulating and motivating. Jiaogulan supposedly helps with energy levels and motivation. Astragulus + Chitosan (for absorption) helps lengthen telomeres (maybe my hair will stop thinning), probably will take with Ginkgo in addition to usual Gotu Kola. Curcumin inhibits the breakdown of Selegiline plus adds its own upper effect. Picamilon is great for getting to sleep, slows down your head for a half hour... but I probably won't need it during the Astragulus therapy. PQQ looks like one hell of a supplement... reviving mitochondria is just one method of staying young.

Exercise and diet aren't really manageable, so please hold back suggestions regarding that for now.

Regimen suggestions, comments, questions? Should I inquire my psychiatrist about any other medicines?

Can I ask you why you only take zinc in the Evening and what benefits you have founds from Methlylene blue and Selegiline and Ashwagandha? Also Pine bark? I have some in my cupboard but I only saw studies where it helped with hyperactivity... I hadn't thought it would help with concentration. I didn't try it for long. I found it made me retain much water, so I stopped taking it.

Can I also probe for the reason why you said exercise is not manageable for you?

[brokenportal]

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[NeuroGuy]

It's been some time now since your last post devinthayer, but do you have any updates? I've found your topics to be very informing, particularly regarding the combination of ginkgo, ginseng and gotu kola.

[fuzza]

Are you doing any physical training? Practiced insight meditation? Are you sleeping ok? Do you think there may be other factors at play than just nutritional/biochemical...?

[gamesguru]

drugs and herbs do way more for me than exercise or food has ever done... by a factor of 10x or greater. There just isn't a comparison. Please, limit advice to the drugs, supplements, and herbs.

Maybe you should contribute to your food bill and make an effort to exercise. The evidence is building that diet and activity play a crucial role in mental health. Check out this article: http://psychcentral....ints/55479.html
Sure, good diet and sufficient exercise won't cure every disease...but unlike bad diet and inactivity, at least they won't worsen your disease or your health.

If you can make it through school without relying on adderall, I think you'll be happier in the end. Stick to the herbs if you really notice a benefit from taking them.

[xks201]

First of all - you are taking a LOT of supplements. No one knows entirely what all of those herbs do. Something like Rhodiola is a DHT inhibitor which would be counterproductive to dopamine production. I bet you didn't know that.

As for taking desmopressin...I would not recommend that. I have a medical condition that forces me to take it. If the average Joe takes it all it is going to do is raise your potassium and dilute your sodium levels, making you feel like a space cadet. I notice next to no cognitive enhancing properties from it. lol

Test your hormones would be my advice if this is that much of an issue. Read into reverse t3...igf-1..testosterone/estrogen ratio.

Not knocking the research you are doing but I used to take a bunch of stuff together like herbs and sometimes the simplest solutions are the best.

Remember ADHD literally is a problem where the dopamine transporter runs backwards and the only things they have found that reverse that backwards leaking transport essentially are ritalin and amphetamine. If you get too jumpy on stims consider adding low dose clonidine.

Edited by xks201, 12 June 2013 - 12:58 PM.

[stablemind]

Any updates OP?