In a study on rats, researchers found that rutin and curcumin together inhibited the development of kidney stones.
The researchers found a significant benefit of rutin/curcumin supplementation on calcium and oxalate levels in the urine. Specifically, Groups 3 and 4 (stone-induced with rutin/curcumin supplementation) had 59% (0.35 vs. 0.86 milligrams in urine every 24 hours) and 77% (0.20 vs. 0.86 mg/24 hours) lower levels of calcium than Group 2 (stone-induced with no supplementation) compared to 105% (0.35 vs. 0.17 mg/24 hours) and 17% (0.20 vs. 0.17 mg/24 hours) higher levels than the control group, indicating an ability of rutin and curcumin to keep calcium at near-normal levels.
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