5 replies to this topic

[kingj24]

So Would the therapeutic benefits remain if I were to try a stimulant with Risperdal? Just the euphoria would be gone am I right?

[kingj24]

I'm on 6mg of Risperdal

[jadamgo]

Combining stimulants and antipsychotics is tricky. The Risperdal can cancel some of the stimulant's effects, but not all of them. It's a powerful D2-like receptor blocker, but a weak D1-like receptor blocker.

In practice, you may find that the risperdal takes the edge off stimulants. They may still improve your ability to focus (if you take a high enough dose), but they may cause less anxiety, motivation, euphoria, alertness, or obsessive thoughts/behaviors.

[kingj24]

So basically they work together you just won't "feel" the medicine am I right? (What I mean by feel is you won't get high off of it)

[jadamgo]

Yeah, that should be what happens. But you never really know until you try.

[medievil]

Risperdal binds stronger to dopamine then dopamine itself wich can inhibit the effects of a stim as the released dopamine cant bind to its receptors; this isnt an issue with weaker ap's as the da can displace it from the ligand.