I posted this elsewhere, but perhaps it needs its own topic:
This very interesting study induced telomerase in mice with modified viruses. They report a 24% increase in lifespan and no increase in cancers.
http://scitechdaily....lifespan-by-24/
Posted 10 December 2012 - 09:31 AM
Posted 10 December 2012 - 12:14 PM
I posted this elsewhere, but perhaps it needs its own topic:
This very interesting study induced telomerase in mice with modified viruses. They report a 24% increase in lifespan and no increase in cancers.
http://scitechdaily....lifespan-by-24/
Given that mice have much longer telomeres compared to humans, it may seem surprising that telomere erosion could contribute to aging and aging associated disorders in this short-lived animal. However, telomeres do erode with advancing age in mice, including in stem cell compartments (Flores et al, 2008), suggesting that telomere shortening and dysfunction also limits growth of mouse cells and consequently contributes to aging.
Finally, we make the novel finding that telomeres shorten with age in different mouse stem cell compartments, which parallels a decline in stem cell functionality, suggesting that telomere loss may contribute to stem cell dysfunction with age.
Edited by Turnbuckle, 10 December 2012 - 12:58 PM.
Posted 12 December 2012 - 11:07 AM
Posted 12 December 2012 - 11:57 AM
Posted 12 December 2012 - 07:27 PM
That might explain some of the life extension effect of c60
Posted 12 December 2012 - 09:12 PM
Call me "Mr. stick in the mud"
That might explain some of the life extension effect of c60
Life extension effect based on a single study of 6 rats. Just a reminder that most health studies are unable to be replicated. I am really hoping that C60 will turn out to be a life/health extension substance, but I am also a realist.
Thanks for posting the study SmithX. I am very surprised at the Telomerase Up-regulating=Cancer meme - how it has remained so strong for so long with scant evidence. I know in theory it makes sense - it is one of those ideas that "clicks" for those familiar with cellular replication and cancer, but it seems like the available science has negated this theory (in non-human models) pretty well, right? Or am I missing a couple of key explosive studies?
Edited by niner, 12 December 2012 - 09:19 PM.
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