36 replies to this topic

[BioFreak]

The benzo was added later on, the problems were already apparent then. They started after she went to the hospital, and they added a opiate for pain management. The benzo was only added recently (2 weeks ago, for only 3 days). It seems like the severity of the symptoms can be magnified through the opiate. If it was the initial cause, thats the question... But if it was a TIA, symptoms should have been better within the first 24h, right?

[BioFreak]

She was not taking any benzo when the problems began, she never had.

Turns out that for most symptoms we experienced, the opiate was the source.

She's now been off the opiate for about 2,5 weeks, no hallucinations anymore, her short term memory got better, and her behavior too. Her hand movements got a lot better too (she is now able to eat soup with a spoon again).

She still displays signs of dementia though (temporal / spacial orientation), and still not good enough short term memory.

We've also stopped noopept for the possible negative effects on short term memory.

We've started uridine stack (without o3 at the moment) a few days ago, so far, her mental abilities seem to improve, even after such a short time. Her emotional response is better too, and she seems to sleep better.

So far, so good.

Edited by BioFreak, 11 May 2013 - 11:54 AM.

[medievil]

Hope she continiues to improve mate.

[socialpiranha]

have you tried galantamine or nicotine patches? in regards to pain has she tried flupirtine? if an opiate is needed, buprenorphine is the best bet as it antagonizes the kappa receptor which is involved in hallucination and is the most potent antidepressant/anxiolytic/mood stabalizer ive ever used.

[Logic]

No ones mentioned Magnesium although there may be enough in the multi?

Lions Mane, and the other shrooms?

See Turnbuckle's profile for info on B3 and MB.

Perhaps AGE blockers/breakers and chelation.

C60oo

Epitalon to get all the glands going.
Telomerase activators?

Deprenyl/Seleligene and a 1 month course of HGH are both supposed to rejuvenate the Thymis, as does Thymelon (spelling?)

She may be low on D3 as she's inside all the time?

[Turnbuckle]

If you search around for beta blocker or metoprolol and the term benzos, you will find some people use beta blockers to help with benzo withdrawal. Beta blockers have a very good safety profile, extend life in some studies and they quiet the flight/fight response. It's not a cure-all, but I think it's a good idea to deal with the constant anxieties.

It would be at the top of my list for a benzo-withdrawal patient.

Beta blockers can also reverse dementia--

Propranolol restores cognitive deficits and improves amyloid and Tau pathologies in a senescence-accelerated mouse model.

Also, nicotinamide--These preclinical findings suggest that oral nicotinamide may represent a safe treatment for AD and other tauopathies...

Edited by Turnbuckle, 13 May 2013 - 11:58 AM.

[Brett Black]

I know you said it likely wasn't Alzheimer's, but I thought I'd share this anyway. There is a hypothesis that herpes simplex virus 1 ("coldsores") may play a role in Alzheimer's. The great majority of elderly people are infected with herpes, even though many dont develop coldsores. Antivirals are a suggested treatment; they are cheap, readily available and considered relatively safe. From what I have read, famciclovir would be the best antiviral for this application:
http://www.tangledne...s_simplex_.html