TLDR: get the pregabalin if you're too deep in the withdrawal and absolutely need a pharmacological option to deal with it,
but if you're getting better: don't worry about adding anything else to make things more complicated. Just ride it out and it'll be over soon. If you do go for pregabalin, personally I wouldn't tell them I'm going through a phenibut withdrawal, I'd just say I lost my perscription [if I really needed it that badly], and that I don't need a full perscription's worth, perhaps just a week's worth of it before I visited my doctor over in BumFukNoWheresVille 50 miles away, but it's up to you.
--------------------
Hmm, well propanolol is something I've always wanted to try but I've heard it can worsen or cause insomnia quite a bit, which I'm guessing you'd want to avoid in this case. (of course if you find it's working for you... I'm happy).
I do think pregabalin is a good phenibut withdrawal option, probably the best. (some say baclofen is, as it's a gaba-b agonist, but I've actually noticed more issues on baclofen than pregabalin, such as mood swings and possible withdrawal.). (Still baclofen was pretty easy to come off of when it was a low dose, so if it'd help then it might be an option).
The reason I think pregabalin is a good option is because as far as I know it doesn't directly agonize gaba-b nor gaba-a receptors, and again I didn't experience a withdrawal from pregabalin. It also is able to relieve some physical anxiety symptoms during the day, even if you took it at night. If you have to be mentally sharp tho im not sure if I'd recommend this one. If you are using it especially for just the sleep aspect of things, being able to feel better at night so you can sleep, I think it's the best option. While the option for sleep initiation may be a low dose of trazodone such as 50mg, good combo.
I'll be honest, I'm not super aware of the entire pharmacology of pregabalin other than that it's a calcium channel blocker and may lower levels of monoamines as well as synaptogenesis and glutamatergic activity in the brain, but although I have never seen anything indicating that it agonizes or stimulates any gaba receptors, oddly it does actually feel like a gaba-b agonist, except, again, without the withdrawal, and also if you're lucky and can get a sweet spot dose, then perhaps mostly none of the negatives.. The feeling on this is a lot warmer and you can easily pass into a deep sleep; it's proven to enhance Slow Wave Sleep
At this point I'm not sure what to say because, it seems you've tapered down to a good low level of phenibut, and I know the withdrawal will feel supremely shitty. Especially the being "hyper vigilante depressed not being able to sleep at all for days" bit. But I think it's safe to say that it will only last for so long and that you don't want to cause many more problems by adding more and more drugs into the mix and causing more and more withdrawal reactions. I'm actually worried about the fact that you took xanax... though maybe you're one of those people who won't really get an adverse reaction from taking it for such short of a time and going off of it. But yeah I really do think pregabalin would be the ticket here, trumps all the other drugs IMO because of the reasons I already stated, and if you have started any kind of xanax withdrawal, then it will trump that too. (sorry guys, I know i probably sound ridiculous saying things like that taking xanax for such a short time would cause any withdrawal, but that kind of thing happens to me acutely so i cant help but be concerned)..
Caveat: I'm just a guy, not a doctor. None of this can be construed as medical advice, as it is not. But I'm being honest with you based on my individual experience with gabaergic withdrawals. (phenibut, lorazepam, etc)
Edited by protoject, 06 December 2013 - 05:47 AM.