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The B5 biotin connection (The question that I think about for over a decade)

acne biotin

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#1 Mens

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Posted 01 December 2013 - 02:34 PM


A lot of brains come here on this forum, a lot of you know way more about this topic than I do. So I thought it be a good place for finding an answer to an old question that keeps me busy for over a decade now. A bit of background that might help others and maybe makes it better to understand my question.. So here we go.

As a teenager I had acne. As most people would, I hated it. It controlled my life pretty much. Just like many I searched on the internet for days and days every now and then. One day, twelve years ago, I found out about B5. On forums people were crazy about it so I ordered B5 from Solgar. A month later I was cured from my acne. It was the most crazy turnaround one could imagine from taking a supplement. In one week my oily skin was gone. My skin sort of peeled a bit and became smooth. From not so healthy looking to a shiny, healthy skin. Every time I think back I still almost can not believe it. I think a lot about how my life would be different if I had not found out and for sure not being were I am today.

I have taken B5 for over ten years almost every day in different doses. Every time I quit supplementing B5 my acne was coming back. One day I was worried about the imbalance of the b vitamins so I started with a B complex. Strange thing was that every time I started B complex supplementations my acne was slowly coming back. A couple years later I started to worry again about imbalance so I decided to buy every b vitamine apart to isolate which (or maybe all) vitamin b caused this.

Not directly expecting an answer but it turned out that I can take all b vitamins without any problems accept biotin. There is something about biotin and I don't think it's only a question of B5 competing with biotin which might also be true at the same time. There are many reports that biotin makes the skin oily which is interesting as well.

I would love to have insight in why biotin might cause acne or if there might be other factors to consider. Any ideas on this topic (the B5+ Biotin connection) are greatly appreciated.

Edited by Mens, 01 December 2013 - 02:35 PM.

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#2 pamojja

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Posted 02 December 2013 - 05:50 PM

Not directly expecting an answer but it turned out that I can take all b vitamins without any problems accept biotin. There is something about biotin and I don't think it's only a question of B5 competing with biotin which might also be true at the same time.


LPI confirms competition between vitamin B5 and biotin only:

Nutrient interactions


Large doses of pantothenic acid (vitamin B5) have the potential to compete with biotin for intestinal and cellular uptake due to their similar structures (37).



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#3 Mens

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Posted 03 December 2013 - 09:36 PM

Interesting, thanks for looking this up.

The original theory for acne and B5 is about the role of B5 in building coenzym A. It seems to me that biotin is a better explanation.
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#4 Heh

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Posted 06 December 2013 - 03:25 AM

Yes, biotin can cause oily skin and acne.

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#5 Mens

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Posted 18 December 2013 - 04:49 PM

Have I found the answer? Biotin IGF-I connection: http://link.springer...0394-009-0773-8





Also tagged with one or more of these keywords: acne, biotin

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