LONGECITY

Great review paper in Nature (pay walled)

Ross FC, Patangia D, Grimaud G, et al. The interplay between diet and the gut microbiome: implications for health and disease. Nat Rev Microbiol. Published online July 15, 2024:1-16.

Diet has a pivotal role in shaping the composition, function and diversity of the gut microbiome, with various diets having a profound impact on the stability, functionality and diversity of the microbial community within our gut. Understanding the profound impact of varied diets on the microbiome is crucial, as it will enable us not only to make well-informed dietary decisions for better metabolic and intestinal health, but also to prevent and slow the onset of specific diet-related diseases that stem from suboptimal diets. In this Review, we explore how geographical location affects the gut microbiome and how different diets shape its composition and function. We examine the mechanisms by which whole dietary regimes, such as the Mediterranean diet, high-fibre diet, plant-based diet, high-protein diet, ketogenic diet and Western diet, influence the gut microbiome. Furthermore, we underscore the need for exhaustive studies to better understand the causal relationship between diet, host and microorganisms for the development of precision nutrition and microbiome-based therapies.

 Screenshot 2024-08-22 094119.png   412.57KB   0 downloads

"...Nonetheless, it is interesting to watch the research community move from identifying specific microbial species that are present in greater numbers in long-lived individuals to trying to figure out exactly what those microbes are doing to increase the odds of living longer...."

https://www.fightagi...g-lived-people/

Wow .. interesting!

https://www.cell.com...14?showall=true

Why is the focus always on Parkinsons when Essential Tremor is far more common by millions? 
 
Anyway, I signed up. Maybe they'll be able to link it to Essential Tremor as well.

 
Hey Nate. You didn't see this?
 

OT: Nate-2004, you may be interested interested in the connection between chronic exposure to the β-carboline harmane and essential tremor. 
 
Laviță et al, 2016. The role of β-carboline alkaloids in the pathogenesis of essential tremor. The Cerebellum, 15(3), pp.276-284.
 
Louis et al, 2007. Blood harmane is correlated with cerebellar metabolism in essential tremor A pilot study. Neurology, 69(6), pp.515-520.
 
Louis et al, 2008. Dietary epidemiology of essential tremor: meat consumption and meat cooking practices. Neuroepidemiology, 30(3), pp.161-166.

Yes yes... better late than never to read this thread.
I recall discussing some very interesting gut bacteria that could be thought of as 24/7 supp manufacturers with you..?
I haven't been able to find that post.

Another reason to have my coffee.

Also related to personalized nutrition and microbiome and health also due to the “…This study reveals a metabolic link between a specific gut microorganism and a specific food item, providing a framework for the understanding of microbial dietary responses at the biochemical level..”

Manghi P, Bhosle A, Wang K, et al. Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts. Nat Microbiol. 2024;9(12):3120-3134. https://www.nature.c...564-024-01858-9

Gut microbiome serves as a “second brain” regulating our bodies

https://actu.epfl.ch...ain-regulating/