4 replies to this topic

[bernax]

http://www.naturalne...rain_cells.html

So this article states that psilocybin is a nootropic. I'd like to know the science behind it, anyone got any scientific ariticles on it?

[Adaptogen]

There are a few studies done by MAPS showing that psilocybin induces neurogenesis.
Beyond that, i don't have much. however, these threads all touch on similar concepts:

http://www.longecity...and-creativity/
http://www.longecity...as-a-nootropic/
http://www.longecity...-transcendence/

[Jeoshua]

Looking at the article linked by the OP, it doesn't seem that study has too much of a leg to stand on, in reguards to the nootropic potential of shrooms.

Mice given low doses of psilocybin stopped reacting to stimulus that untreated mice reacted to. That doesn't mean that the mice "learned" anything. Is it not entirely possible they were just tripping too hard to notice the stimulus?

The studies from MAPS are more promising, and make a certain amount of visceral sense, to me. The mycellia of the mushroom is very close in structure to nerve cells, and they operate in somewhat of a similar way in their growth and interconnection, if not their digestion and other factors. Other studies done on many types of mushrooms, such as Lions Mane, Reishi, and others have shown similar neurotropic abilities, further backing up the idea that the similarity of mycellia and nerve cells can lead to mushrooms providing a nutritive boost to nerve cell production.

Edited by Jeoshua, 29 March 2014 - 09:06 PM.

[koda]

tryptamines are extremely nootropic

They enhance intelligence so much you may find yourself having a conversation with someone & you will almost magically be able to see the thought constructs that put their sentences into place. Very fun to experience, almost like ESP.

How cool would it be if there were pharmacological methods to cause self-synthesis of endogenous DMT?

[knockout_mice]

tryptamines are extremely nootropic

They enhance intelligence so much you may find yourself having a conversation with someone & you will almost magically be able to see the thought constructs that put their sentences into place. Very fun to experience, almost like ESP.

How cool would it be if there were pharmacological methods to cause self-synthesis of endogenous DMT?

Really cool, but tolerance would make it inactive in hours.

I think phenethylamine psychedelics are good "nootropics", but because of the side-effects, like visuals and the emotion-ride, it's hard to use them in most situations. Higher (not [sub-]threshold) doses combined with racetams are very insightful.

Phenethylamines are more stimulating in general, while tryptamines make you rather calm and "stoned". (5-HT1A agonism?!)

Lorcaserin is probably a good less-visual psychedelic. It's a selective 5-HT2C agonist and it's a novel prescription appetite suppressant.